Tobacco Approach Avoidance Training for Adolescent Smokers-2

Phase 2

Completed

• Conditions: Tobacco Use Disorder
• Interventions: Behavioral: AAT-placebo; Behavioral: AAT-experiment

• Registration Number: NCT01625637
• Lead Sponsor: Yale University

Brief Summary

This is a two part study. In Study 2, smokers who want to quit smoking will participate in a 4 week smoking cessation program combining weekly cognitive behavioral therapy (CBT) with weekly regular-AAT or placebo-AAT training. We hypothesize that adolescent smokers will exhibit stronger approach tendencies towards smoking-related stimuli in the tobacco Approach Avoidance Training (AAT) task when compared with nonsmokers and that adolescent smokers who are trained to avoid smoking related stimuli using the AAT will avoid tobacco approach tendencies in the AAT test trials and the Implicit Association Task, when compared to adolescent smokers who are not exposed to AAT training. We also hypothesize that adolescent smokers who are trained to avoid tobacco in a training AAT in combination with CBT will have better abstinence rates compared to those who receive placebo AAT training with CBT.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-05
• Study First Submitted: 2012-06-19
• Study First Submitted QC: 2012-06-20
• Study First Posted: 2012-06-21
• Primary Completion: 2013-05
• Status Verified: 2013-08
• Study Completion: 2013-08
• Last Update Submitted: 2014-01-17
• Last Update Posted: 2014-01-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 66

Inclusion Criteria

• Inclusion Criteria:
• Between ages 13-18 years
• Able to read and write in English.
• Smokers: Smoking 5 or more cigarettes daily for at least 6 months; Baseline urine cotinine levels > 500 ng/ml
• Nonsmokers: Never smokers; Baseline urine cotinine levels < 50 ng/ml

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Exclusion Criteria

• Current criteria for dependence on another psychoactive substance
• Current diagnosis of psychosis, major depression or panic disorder
• Regular use of any psychoactive drugs including anxiolytics and antidepressants unless the medication has been taken consistently for 2 months, is currently being monitored by a physician, and the condition for which the medication is taken is considered to be stable
• Pregnant or lactating girls, based on self report.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
AAT-no contingency continued assessment	AAT-placebo	-
AAT-avoid cigarette condition	AAT-experiment	Adolescent smokers are trained to avoid tobacco in a training AAT

Primary Outcome Measures

Name	Time	Method
Number of cigarettes smoked	4 weeks	To evaluate if retraining automatic approach tendencies towards smoking stimuli, in combination with CBT, enhances an adolescent's ability to quit smoking following 4 weeks of treatment for smoking cessation.

Trial Locations

Locations (1)

Yale University, School of Medicine, Department of Psychiatry; 🇺🇸 New Haven, Connecticut, United States