Anti-inflammatory effect of statins in the human endotoxin model - Statins in Human Endotoxemia

Department of Clinical Pharmacology, Medical University of Vienna0 个研究点目标入组 6 人开始时间: 2005年8月16日最近更新: 2013年5月27日

适应症

试验速览

暂无简介。

•-Men aged between 18 and 45 years
•-Nonsmokers or smokers <10 cig/d
•-Body mass index between 15th and 85th percentile (Must et al. 1991)
•-Normal findings in medical history and physical examination unless the investigator considers an abnormality to be clinically irrelevant
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) no
•F.1.3.1 Number of subjects for this age range

•-Regular use of medication, abuse of alcoholic beverages, participation in a clinical trial in the 3 weeks preceding the study
•-Evidence of hypertension, pathologic hyperglycemia, hyperlipidemia
•-Treatment in the previous 3 weeks with any drug
•-Symptoms of a clinically relevant illness in the 3 weeks before the first study day
•-History or presence of gastrointestinal, liver or kidney disease, or other conditions known to interfere with distribution, metabolism or excretion of study drugs
•-Blood donation during the previous 3 weeks
•-History of hypersensitivity to the trial drug or to drugs with a similar chemical structure

发起方

Department of Clinical Pharmacology, Medical University of Vienna