Effects of Apple polyphenols on carbohydrate and lipid metabolism in Human study : A randomized, double-blinded, placebo-controlled trial
Phase 2
- Conditions
- prediabetes
- Registration Number
- JPRN-UMIN000011751
- Lead Sponsor
- ational Institute of Fruit Tree Science, National Agriculture & Food Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
Not provided
Exclusion Criteria
A person who has regular supplements such as grape seed and tea polyphenols. A person who has participated in other clinical trials in this study at the start. So far, by ingestion of polyphenol and Apple, who has ever complained of a disorder of the body. 1. A person with a history heart failure, myocardial infarction. 2. Treatment of atrial fibrillation, hypertension, arrhythmia, liver failure, renal failure, cerebrovascular disease, arthritis, diabetes, hyperlipidemia, such as anemia. 3. A person have (food, medicine) and allergy history. 4. Pregnant women, nursing mothers 5. Others, who the investigator has determined to be inappropriate as a target for this study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Glucose, insuline
- Secondary Outcome Measures
Name Time Method C-peptide, TNF-a, IL-6, IL-1b, leptin, adiponectin, PAI-1, MCP-1, GLP-1