Skip to main content
Clinical Trials/NCT02080975
NCT02080975
Completed
Not Applicable

Determination of Catheter Contact by Evaluation of Microelectrode Near-Field Signals

David B. De Lurgio2 sites in 1 country20 target enrollmentMarch 2014

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cardiac Catheter Ablation
Sponsor
David B. De Lurgio
Enrollment
20
Locations
2
Primary Endpoint
Correlation between catheter contact and micro electrode signals
Status
Completed
Last Updated
10 years ago

Overview

Brief Summary

Successful radio frequency (RF) cardiac catheter ablation requires the creation of lesions by delivering energy while maintaining adequate catheter contact with the endocardium. Unfortunately, it is difficult to identify contact intraoperatively as a typical RF ablation catheter lacks clear indications of contact. We propose to use the Boston Scientific IntellaTip MiFi catheter to explore whether characteristics of the electrograms produced by the mini-electrodes on the ablation tip could help confirm tissue contact. Using an ultrasound catheter to define instances of clear contact and non-contact, we will determine whether the micro-electrodes produce sufficient information to confirm catheter contact. We propose that the MiFi catheter produces sufficient signal characteristics that can be used as an effective surrogate for adequate tissue contact.

Registry
clinicaltrials.gov
Start Date
March 2014
End Date
December 2015
Last Updated
10 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
David B. De Lurgio
Responsible Party
Sponsor Investigator
Principal Investigator

David B. De Lurgio

Associate Professor

Emory University

Eligibility Criteria

Inclusion Criteria

  • Subject has a diagnosis of typical atrial flutter
  • Subject is clinically indicated for right sided atrial flutter ablation
  • Patient is willing and able to understand and sign the informed consent document
  • Patient is over 18 years of age
  • Patient is willing and able to comply with the study protocol

Exclusion Criteria

  • Patient has one of the following cardiac comorbidities: hypertrophic cardiomyopathy, structural heart disease, congestive heart failure
  • Patient has history of the following arrhythmias: ventricular tachycardia, ventricular fibrillation, Wolff-Parkinson-White syndrome
  • Patient has a contraindication to right atrium ablation, including but not limited to: right atrial thrombus, active systemic infection, or a coagulopathy.

Outcomes

Primary Outcomes

Correlation between catheter contact and micro electrode signals

Time Frame: During Procedure

The known contact state of the ablation catheter will be compared in a blinded fashion to the signals from the microelectrodes to determine if a relationship exits.

Secondary Outcomes

  • Document the electrogram signatures that help demonstrate catheter tip contact(During Procedure)

Study Sites (2)

Loading locations...

Similar Trials