A Prospective, Randomized Clinical Study on the Effects of Casein Phosphopeptide-amorphous Calcium Phosphate (CPP-ACP) Paste on Plaque, Gingivitis and White Spot Lesions in Orthodontic Patients - Part 2

Not Applicable

Completed

• Conditions: Early Caries Lesions
• Interventions: Device: CPP-ACP (GC Tooth Mousse); Device: Fluoride (Elmex Medical Gel); Device: CPP-ACP (GC MI Paste Plus)

• Registration Number: NCT00670618
• Lead Sponsor: University Hospital, Ghent

Brief Summary

Influence of CPP-ACP paste and Elmex Medical Gel on the prevention of white spot lesions in orthodontic patients during fixed appliances.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2008-04-30
• Study First Submitted QC: 2008-05-01
• Study First Posted: 2008-05-02
• Study Start: 2008-10-01
• Primary Completion: 2011-01-21
• Study Completion: 2011-04-26
• Status Verified: 2023-05
• Last Update Submitted: 2023-05-08
• Last Update Posted: 2023-05-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 325

Inclusion Criteria

• No white spot lesion at the time of placement of fixed appliances

Exclusion Criteria

• White spots already present before start orthodontic treatment

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1	CPP-ACP (GC Tooth Mousse)	CPP-ACP (GC Tooth Mousse)
3	Fluoride (Elmex Medical Gel)	Fluoride (Elmex Medical Gel)
2	CPP-ACP (GC MI Paste Plus)	GCC-ACP (GC MI Paste Plus)

Primary Outcome Measures

Name	Time	Method
Prevention of the opacity of white spots during orthodontic treatment with fixed appliances	After 2 years

Trial Locations

Locations (1)

University Hospital Ghent; 🇧🇪 Ghent, Belgium