Endogenous Pain Modulation in Patients with Shoulder Arthroplasty for Osteoarthritis

Recruiting

• Conditions: 10023213; degenerative joint disease; Osteoarthritis

• Registration Number: NL-OMON53872
• Lead Sponsor: Reinier Haga Orthopedisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 25

Inclusion Criteria

- Age >= 18 yrs
- Scheduled to undergo primary total shoulder arthroplasty (TSA) or reversed
shoulder arthroplasty (RSA) for primary shoulder osteoarthritis or cuff tear
arthropathy
- American Society of Anesthesiologists score 1, 2 or 3
- Able to provide written informed consent

Exclusion Criteria

- Regular use of anti-depressants or anti-epileptics for any purpose, including
SNRIs and gabapentinoids
- The presence of any chronic pain disorder other than osteoarthritis
- Osteoarthritis in joints other than the affected shoulder, for which
arthroplasty is/will be planned in the near future
• Difficulty with or inability to perform psychophysical testing (eg. in case
of cognitive or psychiatric disorders)
- Difficulty with or inability to communicate with the investigators (eg.
difficulty with the Dutch language, cognitive/memory disorders)

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameters are CPM and TS values at baseline and at 3 and 6<br /><br>months after surgery, as well as the absence/presence of allodynia at baseline<br /><br>and at 3 and 6 months after surgery.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary outcomes are painscores, pain catastrophizing and coping strategies<br /><br>at baseline and at 3 and 6 months after surgery.</p><br>