Record Voxel Rate Nonlinear Optical Microscope to Unravel Brain Connectome and Signaling-Establish Reliably Electrophysiological Readouts From Human-induced Pluripotent Stem Cells (hiPSCs)-Derived Cerebral Organoids and Surgically Dissected Human Live Brains
Not Applicable
Recruiting
- Conditions
- Brain DiseasesBrain Tumor
- Registration Number
- NCT05921786
- Lead Sponsor
- National Taiwan University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
Inclusion Criteria:<br><br> 1. Patients older than the age of 18 with diagnosis of brain disease (both<br> newly-diagnosed or recurrent) who are suitable and willing to receive resection<br> surgery.<br><br>Exclusion Criteria:<br><br> 1. Patients who cannot give consent to participate in the study.<br><br> 2. The tumor samples failed to give a conclusive pathological diagnosis by standard<br> pathological workflow.<br><br> 3. Patients who only receives biopsy surgery rather than resection surgery.<br><br> 4. Significant post-irradiation effect or radiation necrosis reported in the<br> pathological examination.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Acquire neuronal structual (image frame) results of different brain regions;Acquire electrophysiological readout (voltage amplitude, mV) datas of different brain regions
- Secondary Outcome Measures
Name Time Method To conduct imaging for multiple types of human brain tissues and construct the neuron image database