actobacilli associated with antibiotics in the treatment of periodontitis in smokers

Phase 2

• Conditions: Chronic Periodontitis; Smokers; C25.775.912; K05.3

• Registration Number: RBR-55bc85
• Lead Sponsor: niversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araçatuba

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-03-06
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Patients aged between 30 and 70 years old; diagnosis of severe generalized chronic periodontitis; heavy smokers (more than 10 cigarettes per day for more than 5 years) and at least 15 teeth in mouth, excluding third molars.

Exclusion Criteria

Medical disorders that require antibiotic prophylaxis or who could influence the response of the treatment; having received treatment for periodontal scaling and root planing in the last 6 months; having consumed drugs that affect the periodontal tissues in the last 6 months (antibiotics, anti-inflammatory drugs, anticonvulsants, immunosuppressants or calcium channel blockers); pregnancy; prosthetic rehabilitations extensive carrier; in orthodontic treatment; patients with metabolic disorders such as diabetes; immune disorders; alcohol and illicit drug use.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Clinical attachment gain, within 6 months, this was verified by periodontal probing with clinical insertion level and data tabulation for mean reduction analysis of at least 1mm.

Secondary Outcome Measures

Name	Time	Method
Probing depth reduction, visible plaque index, bleeding on probing, gingival recession, number of residual pockets within 6 months, verified by periodontal probing with clinical insertion level and data tabulation for mean reduction analysis.