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Central airways mechanics

Conditions
tracheobronchomalacia (TBM) tracheabronchomalacieCentral airway mechanics
Registration Number
NL-OMON28602
Lead Sponsor
ErasmusMC/ Sophia
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
60
Inclusion Criteria

•Indication for bronchoscopy as decided by the treating paediatric chest physician;

•Aged 6 years or above;

Exclusion Criteria

•Any contraindications to MRI

•In the case any contra indications to administering bronchodilator, this part of the protocol will be omitted

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
sensitivity and specificity of MRI as a diagnostic tool to assess central airway collapsibility
Secondary Outcome Measures
NameTimeMethod
to assess concordance between MRI and bronchoscopy<br>airway lumen reduction scores of both MRI and bronchoscopy to assess associations between MRI/ bronchoscopy scores and pulmonary function test (PFT) parameters
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