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central airways and lung volume assessment by Magnetic Resonance Imaging in childre

Recruiting
Conditions
10038686
10010613
astma cystic fibrosis
Registration Number
NL-OMON41163
Lead Sponsor
Erasmus MC, Universitair Medisch Centrum Rotterdam
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
36
Inclusion Criteria

•Age between 8 - 18 years;
• Clinical diagnosis of CF confirmed by a positive sweat test or two CF-related mutations OR
• Clinical diagnosis of asthma as confirmed by treating physician OR;
• Healthy child as determined by no history of respiratory disease or congenital deformities.
• Ability to perform lung function tests.
• Written informed consent from parents/caregivers

Exclusion Criteria

•Inability to follow instructions of the investigator
•Claustrophobia
•Any clinical condition which, according to the treating physician, might put the patient at risk
•For CF patients: respiratory tract infection requiring IV antibiotics in the last 4 weeks
•For asthma patients: exacerbation requiring a course of oral corticosteroids in the last 4 weeks
any question answered with YES on the MRI questionnaire on contra indications

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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