Changes of blood volume and physiological parameters after infusion of HES or crystalloid: a randomized-controlled study

Not Applicable

• Conditions: Perioperative patients

• Registration Number: JPRN-UMIN000024314
• Lead Sponsor: Department of Anesthesiology, Tohoku University Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-10-06
• Study Completion: 2017-05-25
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Not provided

Exclusion Criteria

Patients with, hemorrhage, dehydration, body weight (BW) < 35 kg or > 95 kg, cardiovascular disease, pulmonary disease, renal disease, diabetes mellitus, and/or mean arterial blood pressure < 40 mmHg at the baseline measurement.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Increases of blood volume and the blood pressure at 10 minutes after the completion of administration of 500 mL of 130 HES, 70HES or bicarbonate Ringer's solution.

Secondary Outcome Measures

Name	Time	Method
Changes of heart rate, peripheral perfusion index and oxygenation at 10 minutes after the acompletion of administration of 500 mL of 130 HES, 70HES or bicarbonate Ringer's solution.