Continuous EMG Measurements in Children With Asthma During Sleep

Not yet recruiting

• Conditions: Sleep-Disordered Breathing; Asthma in Children; Electromyography

• Registration Number: NCT05547477
• Lead Sponsor: Medisch Spectrum Twente

Brief Summary

The objective of this study is to investigate whether electromyography of the diaphragm during sleep in asthmatic children can be used to objectively monitor asthma control.

Detailed Description

Not available

Study Timeline

• Status Verified: 2022-09
• Study Start: 2022-09
• Study First Submitted: 2022-09-09
• Study First Submitted QC: 2022-09-16
• Last Update Submitted: 2022-09-16
• Study First Posted: 2022-09-21
• Last Update Posted: 2022-09-21
• Primary Completion: 2022-12
• Study Completion: 2023-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Paediatrician diagnosed asthma or bronchial hyperresponsiveness
• Aged 4 till 18
• Admitted to the paediatric ward of Medisch Spectrum Twente

Exclusion Criteria

• Admittance to the ICU
• Patient has ICD or pacemaker
• Parents and/or patient cannot understand or speak Dutch
• Does not fit in one of the available Hexoskin shirts

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Breathing registration in sleep using electromyography	From admittance to the ward, up to 12 hours	Amplitude of the EMG signal will be used to obtain breathing waveforms.

Secondary Outcome Measures

Name	Time	Method
Prediction of asthma exacerbations	After inclusion of all subjects, up to 3 months	A machine learning model will be applied to be able to predict an asthma exacerbation before it occurs