Perioperative Geriatrics Intervention for Older Cancer Patients Undergoing Surgical Resection
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Pancreatic Cancer
- Sponsor
- Massachusetts General Hospital
- Enrollment
- 160
- Locations
- 1
- Primary Endpoint
- Hospital Length Of Stay
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
The purpose of this research study is to addresses the challenge of managing the unique perioperative needs of older cancer patients undergoing surgical resection.
Detailed Description
In the proposed study, the investigators will conduct a randomized controlled trial of a perioperative geriatrics intervention versus usual care in older patients with gastrointestinal (GI) cancers undergoing surgical resection. The perioperative geriatrics intervention will entail pre- and post-operative geriatric care for patients age ≥65 undergoing surgery for gastrointestinal cancers. Specifically, geriatric clinicians will evaluate and manage patients preoperatively in the outpatient setting and postoperatively in the inpatient setting as a consultant. The investigators will evaluate the effect of the perioperative geriatrics intervention on postoperative length of stay (primary outcome) and readmissions in a sample of 160 patients. The investigators will also assess the impact of the perioperative geriatrics intervention on patient-reported outcomes, including quality of life (QOL) and symptom burden. The study will take place at Massachusetts General Hospital.
Investigators
Ryan Nipp
MD
Massachusetts General Hospital
Eligibility Criteria
Inclusion Criteria
- •Age 65 or older
- •Diagnosed with pancreatic, esophageal, rectal, colon, hepatobiliary, or gastric cancer (including patients with prior diagnosis of another cancer)
- •Planning to receive surgical resection at MGH (including both curative and palliative resections)
- •Verbal fluency in English
Exclusion Criteria
- •Unwilling or unable to participate in the study
- •Significant uncontrolled psychiatric disorder (e.g. psychotic disorder, bipolar disorder, major depression) or other co-morbid disease (e.g. dementia, cognitive impairment) which the treating clinician believes prohibits informed consent or participation in the study
Outcomes
Primary Outcomes
Hospital Length Of Stay
Time Frame: 2 years
Hospital length of stay from admission to discharge
Secondary Outcomes
- 30-day readmission rate(2 years)
- Time to readmission(2 years)
- Change In patients' QOL From Baseline To Post-Intervention(For all patient-reported outcomes, change from baseline to post-intervention is defined as change from baseline to post-operative day 5 (±1 day) and from baseline to post-operative day 30 (±7 days)])
- Change In Patients' Symptom Scores From Baseline To Post-Intervention(For all patient-reported outcomes, change from baseline to post-intervention is defined as change from baseline to post-operative day 5 (±1 day) and from baseline to post-operative day 30 (±7 days)])
- Change In Patients' Depression From Baseline To Post-Intervention(For all patient-reported outcomes, change from baseline to post-intervention is defined as change from baseline to post-operative day 5 (±1 day) and from baseline to post-operative day 30 (±7 days)])
- Rates Of Post-Intervention Depression Symptoms(For all patient-reported outcomes, change from baseline to post-intervention is defined as change from baseline to post-operative day 5 (±1 day) and from baseline to post-operative day 30 (±7 days)])
- Rates Of Post-Intervention Moderate/Severe Symptoms(For all patient-reported outcomes, change from baseline to post-intervention is defined as change from baseline to post-operative day 5 (±1 day) and from baseline to post-operative day 30 (±7 days)])
- Change In Activities of Daily Living (ADLs) / Instrumental Activities of Daily Living (IADLs) From Baseline To Post-Intervention(For all patient-reported outcomes, change from baseline to post-intervention is defined as change from baseline to post-operative day 5 (±1 day) and from baseline to post-operative day 30 (±7 days)])
- Change In The Number Of Falls During The Past 6 Months (measured continuously) From Baseline To Post-Intervention.(For all patient-reported outcomes, change from baseline to post-intervention is defined as change from baseline to post-operative day 5 (±1 day) and from baseline to post-operative day 30 (±7 days)])
- Rates Of Post-Intervention Activity of Daily Living (ADL) Deficits(For all patient-reported outcomes, change from baseline to post-intervention is defined as change from baseline to post-operative day 5 (±1 day) and from baseline to post-operative day 30 (±7 days)])
- Rates Of Post-Intervention Instrumental Activity of Daily Living (IADL) Deficits(For all patient-reported outcomes, change from baseline to post-intervention is defined as change from baseline to post-operative day 5 (±1 day) and from baseline to post-operative day 30 (±7 days)])
- Rates Of Post-Intervention Falls(For all patient-reported outcomes, change from baseline to post-intervention is defined as change from baseline to post-operative day 5 (±1 day) and from baseline to post-operative day 30 (±7 days)])