Evaluation of the Relationship Between Mediterranean Diet and Menopausal Symptoms in Postmenopausal Women

Completed

• Conditions: Menopausal Complaints

• Registration Number: NCT06755255
• Lead Sponsor: Marmara University Pendik Training and Research Hospital

Brief Summary

This cross-sectional study aimed to evaluate the relationship between the frequency and severity of postmenopausal symptoms in women aged 45-65 years and the level of compliance with the Mediterranean diet, and the main question it aimed to answer is: Do women with higher compliance with the Mediterranean diet have milder symptoms?

Detailed Description

This cross-sectional study was conducted between 01.01.2024 and 01.06.2024 with women aged 45-65 who were registered at Tuzla E-ASM affiliated with Marmara University Pendik Hospital and who had been in menopause for at least 1 year. The sample size was calculated as 272 and the target number was determined as 305. After obtaining written consent from the participants who agreed to participate in the study and met the inclusion criteria, a questionnaire form was applied to these individuals, which questioned their sociodemographic characteristics, age of menstruation onset, pregnancy history, smoking and alcohol use, use of supplements, Mediterranean Diet Adherence Scale (MEDAS) and Menopause Rating Scale (MRS). The presence, type and severity of menopausal symptoms with the Mediterranean diet were evaluated.

Study Timeline

• Study Start: 2024-01-01
• Primary Completion: 2024-08-01
• Study Completion: 2024-09-01
• Status Verified: 2024-11
• Study First Submitted: 2024-11-19
• Study First Submitted QC: 2024-12-23
• Last Update Submitted: 2024-12-23
• Study First Posted: 2025-01-01
• Last Update Posted: 2025-01-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 305

Inclusion Criteria

• Those who volunteered to participate in the study,

Exclusion Criteria

• Those with a diagnosed eating disorder,
• Those using medication for obesity,
• Those with a chronic metabolic disease that is not receiving treatment and whose values related to the disease are not regulated (pronounced hypo/hyperthyroidism, uncontrolled diabetes, etc.),
• Those with a mental or physical condition that prevents communication (some neuropsychiatric diseases and mental retardation),
• Those who do not understand and/or speak Turkish,
• Those who do not give consent to participate in the study, •-Those who are currently using any hormonal supplements to prevent or reduce menopausal symptoms were excluded from the study.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mediterranean diet adherence and menopausal symptoms association	Data collected at a single time point upon participants' enrollment.	Mediterranean diet adherence total score and menopausal rating scale total score were inversely and weakly correlated with each other (p\<0.01; r= -0.295).

Secondary Outcome Measures

Name	Time	Method
Menopausal symptom severity in women with low and dietary adherence	Data collected at a single time point upon participants' enrollment.	Women with mild menopausal symptoms had the highest adherence score with the Mediterranean diet, while women with severe symptoms had the lowest adherence score to the Mediterranean diet (p\<0.01).
Vasomotor menopausal symptom severity in women with low dietary compliance	Data collected at a single time point upon participants' enrollment.	Mediterranean diet adherence scores were lower in the group with severe vasomotor symptoms. (p\<0,05)
Psychological menopausal symptom severity in women with low dietary compliance	Data collected at a single time point upon participants' enrollment.	Mediterranean diet adherence scores were lower in the group with severe psychological symptoms.
Urogenital menopausal symptom severity in women with low dietary compliance	Data collected at a single time point upon participants' enrollment.	There is no significant relationship between urogenital symptom scores and Mediterranean diet compliance scores.

Trial Locations

Locations (1)

Marmara University- Tuzla Eğitim ASM; 🇹🇷 İstanbul, Tuzla, Turkey