JPRN-UMIN000012014
Completed
未知
Exploratory clinical trial of serum-, and feeder cell-free cultivated autologous corneal limbal epithelial cell sheet transplantation using human amniotic membrane for corneal epithelial stem-cell deficiency - Xeno-free cultivated corneal limbal epithelial cell sheet transplantation
Department of Ophthalmology, Graduate School of Medicine, The University of Tokyo0 sites3 target enrollmentOctober 10, 2013
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- nilateral corneal epithelial stem cell deficiency: Patients who have dysfunction of the entire limbus with almost replaced by conjunctival epithelium, neovascularization and corneal scarring tissue.
- Sponsor
- Department of Ophthalmology, Graduate School of Medicine, The University of Tokyo
- Enrollment
- 3
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •1\) Subjects who are pregnant, plan to become pregnant, or are breast\-feeding. 2\) Subjects who have systemic infections (HBV, HCV, HIV, HTLV\-1\) 3\) Subjects who have extremely severe dry eye 4\) Subjects who has not passed for six months after undergoing the next operation on the eye which is due to be transplanted; conjunctival sac plasty, amnion transplant of sclera, mitomycin\-C treatment 5\) Subjects who are not unsuitable for this project by some complications (judged by the docter in charge).
Outcomes
Primary Outcomes
Not specified
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