A comparison of the effect of oral Curcumin and Prednizolon on pain relief and size of the lesions in patients with Oral Lichen Planus lesions who refer to OMF center of Dental University of Gilan and private office in Rasht 1396-97
Phase 3
Recruiting
- Conditions
- Oral Lichen Planus.Lichen planus
- Registration Number
- IRCT20100101002950N5
- Lead Sponsor
- Rasht University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 56
Inclusion Criteria
Patients with Oral lichen planus(confirmed by clinical examination, biopsy and histopathological evaluation)
Exclusion Criteria
Pregnancy
Breastfeeding
Patients who take corticosteroid
Patients with increased hepatic enzyme and patients who take anti coagulation and anti platelet drug, like Warfarin.
Orthodontic appliences
Patients with Peptic ulcer, Gall-bladder stone
Existance of any neoplasms or viral infections
Receiving topical treatment for OLP during last 2 weeks or systemic treatment of OLP during last 4 weeks
Consumption of Azathioprine, Cyclosporine, UVA,PUVA or UVB during last month
The presence of allergies to Corticosteroids or herbal drugs like Curcumin
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of pain. Timepoint: Before treatment and 1,2,4 week after treatment. Method of measurement: Use of Visual Analogue Scale(VAS).
- Secondary Outcome Measures
Name Time Method Size of the Lichen planus lesions. Timepoint: Before treatment and 1,2,4 week after treatment. Method of measurement: Tongprasom scale(0-5).