Preload versus coload of ringer lactate to prevent hypotension during elective cesarean section under spinal anesthesia

Phase 3

Recruiting

• Conditions: Hypotension during cesarean section.; Hypotension

• Registration Number: IRCT20110313006044N5
• Lead Sponsor: Vice-Chancellery for Research Hormozgan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 4 April 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Age 18-45 years
Singleton term pregnancy
Elective cesarean section
Spinal anesthesia
American Society of Anesthesiologists (ASA) class I or II

Exclusion Criteria

Twin or multiple pregnancy
ASA class above II
Hypertension or cardiovascular diseases
Contraindications of spinal anesthesia
Hypersensitivity to bupivacaine
Renal disorders
Severe hemorrhage during surgery requiring blood transfusion
Uterine atony requiring hysterectomy
Block failure or incomplete block demanding extra anesthetics

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Maternal blood pressure. Timepoint: Baseline, immediately after spinal anesthesia, then at 2, 4, 6, 8, 10, 15, 20, 25, 30, 40, 50, and 60 min after spinal anesthesia and in the recovery unit. Method of measurement: Monitoring device.

Secondary Outcome Measures

Name	Time	Method
Maternal mean arterial pressure. Timepoint: Baseline, immediately after spinal anesthesia, then at 2, 4, 6, 8, 10, 15, 20, 25, 30, 40, 50, and 60 min after spinal anesthesia and in the recovery unit. Method of measurement: Monitoring device.;Maternal heart rate. Timepoint: Baseline, immediately after spinal anesthesia, then at 2, 4, 6, 8, 10, 15, 20, 25, 30, 40, 50, and 60 min after spinal anesthesia and in the recovery unit. Method of measurement: Monitoring device.;Maternal oxygen saturation. Timepoint: Baseline, immediately after spinal anesthesia, then at 2, 4, 6, 8, 10, 15, 20, 25, 30, 40, 50, and 60 min after spinal anesthesia and in the recovery unit. Method of measurement: Monitoring device.;Neonatal Apgar score. Timepoint: 1 and 5 min after delivery. Method of measurement: Clinical assessment.