Change in olfactory perception during psychotherapeutic treatment of patients with depressive disorder

Recruiting

• Conditions: F32; F33; Depressive episode; Recurrent depressive disorder

• Registration Number: DRKS00012970
• Lead Sponsor: niversität des SaarlandesKlinische Psychologie und Psychotehrapie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-10-24
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Patient sample: Depressive disorder as primary diagnosis, participation in cognitive behavioral therapy

Control group: healthy volunteers

Exclusion Criteria

Patients: Drug or substance abuse, permanent use of medication (exception: oral contraceptives or occasional use of headache tablets up to one week before the beginning of the study, prescribed psychopharmaceuticals)

Control group: Mental disorder, drug or substance abuse, permanent administration of medications (exception: oral contraceptives or occasional use of headache tablets up to one week before the start of the study)

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Examination of the presence of deficits in olfactory perception (perception threshold, discrimination, identification) in patients with depression compared to a healthy control group adjusted for age and sex. The olfactory perception is measured in all dimensions with the Sniffin 'Sticks.<br><br>Change of the olfactory perception (perception threshold, discrimination, identification) in the course of the therapy.<br><br>Predictability of the change in symptom stress, recorded by the BDI, in the course of the therapy based on the olfactory perception.<br><br>Three survey days: 1) before the start of therapy (during or after the probatory sessions), 2) after the 12th therapies session, 3) after the 24th therapies session.

Secondary Outcome Measures

Name	Time	Method
Diagnostic Interview using SKID. Examination of the correlation between olfactory performance and the severity of comorbidities like e.g. anxiety disorders (BSI).