Dietary energy density and type 2 diabetes
Phase 2
- Conditions
- diabetes.????? ??? 2 ? ???? ?????????? ??????? ??? ?????? ??????? ??? 2
- Registration Number
- IRCT201105281485N4
- Lead Sponsor
- Vice chancellor for research,Isfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 60
Inclusion Criteria
Diabetic non-pregnant and non-lactating females aged 30-60 y, Lack of insulin injection, non-smokers, lack of having a special diet except for usual diabetes meal plan, lack of sever weight loss in the last 3 months, not having sever infection in the last 3 months, trauma, surgery, hypo- and hyper-thyroidism, lack of the use of vasodialators, antioxidant supplements, vitamin and mineral supplements, diuretics, betablockers, garlet, OCP, aspirine and corticosteroids.
Exclusion criteria: Lack of adherence to the prescribed diet, starting the use of above-mentioned medications or affecting by the above-mentioned diseases, alterations in dosage and type of current medications, getting pregnant
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum visfatin level. Timepoint: before the intervention week 8. Method of measurement: Enzyme-Linked Immunosorbent Assay (ELISA) ?ng/dL.;Serum adiponectin level. Timepoint: before the intervention week 8. Method of measurement: Enzyme-Linked Immunosorbent Assay (ELISA) ?ug/dL.;Serum chemerin level. Timepoint: before the intervention week 8. Method of measurement: Enzyme-Linked Immunosorbent Assay (ELISA) ?ng/dL.;Serum high sensitive Interleukin 6 (hs IL-6) levels. Timepoint: before intervention and week 8. Method of measurement: Enzyme-Linked Immunosorbent Assay (ELISA) ?ng/dL.;Serum high sensitive tumor necrosis factor-alpha (hs TNF-a) levels. Timepoint: before intervention and week 8. Method of measurement: Enzyme-Linked Immunosorbent Assay (ELISA) ?mg/dL.;Serum high sensitive-C Reactive Protein (hs-CRP) levels. Timepoint: before the intervention week 8. Method of measurement: high sensitive immunoturbidimetry, mg/dL.
- Secondary Outcome Measures
Name Time Method