THE MUSCLE POWER STUDY: Surgery related muscle loss and muscle strength after complex abdominal surgery for pseudomyxoma peritonei, pancreatic, liver and colorectal cancer

Recruiting

Conditions: • pseudomyxoma peritonei (PMP)• liver tumor (primary cancer or colorectal liver metastases)• pancreatic cancer• bile duct cancer • colorectal cancer

Registration Number: NL-OMON28560

Lead Sponsor: This work is supported by a grant from the UMCG Cancer Research Foundation (Institutional Foundation for Cancer Research and Development). The study protocol has not undergone any peer-review by this funding body, nor will they play a role in the analysis and interpretation of the data.

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Not specified

Target Recruitment: 178

Inclusion Criteria

In order to be eligible to participate in this study, a patient must meet all of the following inclusion criteria:
•Age = 18 years;
•Able to read and understand the Dutch language;
•Diagnosed or the suspicion of a liver tumor (primary cancer or colorectal liver metastases), pancreatic malignancy, bile duct malignancy, colon tumor, rectum tumor, or pseudomyxoma peritonei;
•Scheduled to undergo elective open major abdominal surgery at UMCG, consisting of the following surgical procedures:
ocytoreductive surgery combined with hyperthermic intraperitoneal intraoperative chemotherapy (CRS with HIPEC);
o(sub)total pelvic exenteration;
opylorus preserving pancreaticoduodenectomy (PPPD);
owhipple procedure (classic pancreaticoduodenectomy);
o(sub)total pancreatectomy; or
omajor liver resection defined as =3 liver segments.
•Presence of a preoperative computed tomography (CT) of the abdomen to determine sarcopenia preoperatively;
•Has given informed consent to participate in the study.

Exclusion Criteria

A potential eligible patient who meets any of the following exclusion criteria will be excluded from participation in this study:
•Scheduled to undergo emergency resection;
•Scheduled to undergo laparoscopic surgery;
•Scheduled to undergo minor liver resections (defined as <3 liver segments);
•Inability to co-operate and give informed consent.