Comparative study of the influence of blood flow, oxygenation and hemodynamics generated during the use of extracorporeal circulation machine
- Conditions
- heart failure, coronary insufficiency, myocardial infarctionC14.280.647.187.150
- Registration Number
- RBR-48x3xv
- Lead Sponsor
- Instituto Nacional de Cardiologia
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- data analysis completed
- Sex
- Not specified
- Target Recruitment
- Not specified
Patient admitted to the National Institute of Cardiology, which have coronary heart disease and were referred for surgery for isolated primary CABG, patients with ejection fraction greater than or equal to 45%, both sexes; aged between 18 and 75 years, during cardiopulmonary bypass use of vacuum-assisted venous drainage and use of normothermia during cardiopulmonary bypass
Patient admitted to the National Institute of Cardiology, which appear as disease and / or diagnosis associated with surgery, recent myocardial infarction (less than 3 months), recent stroke (less than 3 months, unstable angina, urgent or emergency surgery, diabetes mellitus decompensated - disease of diabetic ketoacidosis, renal failure - creatinine clearance <30 ml / min
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Decline in value of lactate during cardiopulmonary bypass in at least 30%.<br> Normal value of lactate less than 3 mmol / L<br>
- Secondary Outcome Measures
Name Time Method The oxy-hemodynamic variables, oxygen delivery (350 to 450 mL/min/m2), oxygen consumption (90 mL/min/m2), mixed venous oxygen saturation (70 to 80%), venous blood carbon dioxide gradient carbon (less than 10 mmHg) and arteriovenous difference of pH (less than 0.1), must be within these values ??so that tissue perfusion is adequate.<br>