Familial Factors in the Development of Colon Cancer

Alliance for Clinical Trials in Oncology1 site in 1 country600 target enrollmentDecember 2001

ConditionsColorectal Cancer

Overview

Phase: N/A
Intervention: Not specified
Conditions: Colorectal Cancer
Sponsor: Alliance for Clinical Trials in Oncology
Enrollment: 600
Locations: 1
Status: Completed
Last Updated: 9 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

RATIONALE: Genetic studies may help in understanding the genetic processes involved in the development of some types of cancer.

PURPOSE: Clinical trial to study the cancer-related genes in patients who have colon cancer or adenomatous polyps.

Detailed Description

OBJECTIVES: * Identify human colon neoplasia susceptibility genes in patients with colon cancer or adenomatous polyps. * Correlate the inheritance of novel susceptibility alleles for adenomatous polyposis of the colon with colon neoplasia in these patients. * Correlate colon neoplasia susceptibility with the presence of COX-2, sPLA2, and DNMT genes in these patients. * Identify a novel gene that governs increased susceptibility to colon adenoma and cancer in the genome of these patients.

Registry

clinicaltrials.gov

Start Date

December 2001

End Date

October 2010

Last Updated

9 years ago

Study Type

Observational

Sex

All