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Assessment of the Safety and Efficacy of Ciproxan-I.V. in Daily Clinical Practice - Analysis Results From a Post-marketing Surveillance

Completed
Conditions
Infection
Interventions
Registration Number
NCT01670435
Lead Sponsor
Bayer
Brief Summary

This study is a post-marketing surveillance in Japan, and it is a local prospective and observational study of patients who have received Ciproxan intravenously as a first-line treatment for sepsis, secondary skin infections followed by superficial burn, post-surgical or post-traumatic, pneumonia, peritonitis, cholecystitis, cholangitis, anthrax. The objective of this study is to assess safety and efficacy of Ciproxan in daily clinical practice. A total of 3,000 patients are to be enrolled and assessed during the period of treatment with Ciproxan.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
3274
Inclusion Criteria
  • Patients who received Ciproxan as a first-line treatment were eligible for the study, among those with sepsis, secondary infection due to trauma, burn, or surgical wound, pneumonia, peritonitis, cholecystitis, cholangitis, and anthrax as the indications of this drug.
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Exclusion Criteria
  • Patients who are contraindicated based on the product label.
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Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Group 1Ciprofloxacin (BAYQ3939)-
Primary Outcome Measures
NameTimeMethod
Incidence of adverse drug reactions (ADRs) and serious adverse events (AEs)After 9 days
Clinical efficacy by four grade (Response, Minor Response, No Response, and Indeterminable) at an investigator discretionAfter 9 days
Secondary Outcome Measures
NameTimeMethod
ADR incidence rates classified by patient's background factorsAfter 9 days
Efficacy rates classified by patient's background factorsAfter 9 days
Efficacy rate calculated with Response and Minor Response considered as responderAfter 9 days
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