Impact of Bariatric Surgery on Women Fertility

Completed

• Conditions: Fertility Issues
• Interventions: Procedure: Sleeve gastrectomy

• Registration Number: NCT05457413
• Lead Sponsor: Ain Shams University

Brief Summary

Obesity is a multifactorial risk factor for subfertility, in relation to chronic hormonal change induced by adipose tissue. This prospective cohort study aims to evaluate the impact of bariatric surgery induced weight loss on women fertility.

Detailed Description

Females undergoing sleeve gastrectomy will be assessed for improvement of fertility indicators

Study Timeline

• Study First Submitted: 2022-07-05
• Study First Submitted QC: 2022-07-13
• Study First Posted: 2022-07-14
• Study Start: 2022-07-25
• Primary Completion: 2022-12-01
• Status Verified: 2023-01
• Study Completion: 2023-03-01
• Last Update Submitted: 2023-04-17
• Last Update Posted: 2023-04-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 75

Inclusion Criteria

• Age from 20-40 years.
• BMI >35 kg/m2

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Exclusion Criteria

• Women with medical endocrinal disorders as DM, thyroid, hyperprolactinaemia, etc.
• Women using any hormonal treatment or fertility drugs like oral contraceptive pills and/or metformin.
• Women have any surgical complication intra-operatively or post operatively.
• Women refused to participate in the study.

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Sleeve gastrectomy	Sleeve gastrectomy	Sleeve gastrectomy for weight loss

Primary Outcome Measures

Name	Time	Method
Change in Antimullerian hormone level	3 months	Change in antimullerian hormone level

Secondary Outcome Measures

Name	Time	Method
Change in serum LH level	3 months
Change in serum FSH level	3 months

Trial Locations

Locations (1)

Ain Shams University Maternity Hospital; 🇪🇬 Cairo, Cairo/القاهرة, Egypt