Blood changes seen in COVID positive/suspect surgical patients: An observational study
Not Applicable
- Conditions
- Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhereHealth Condition 2: O- Medical and Surgical
- Registration Number
- CTRI/2022/04/042003
- Lead Sponsor
- AIIMS Rishikesh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.COVID Positive patients
2.American Society of Anesthesiologist Grade I-III
3.Patient undergoing surgery
Exclusion Criteria
1.Any contraindication to general anesthesia/regional/spinal anaesthesia
2.Patients on recent chemotherapy/radiotherapy(past 15 days).
4.Patient on chronic treatment with steroids or immune-suppressants.
5.Patient who are morbidly obese, have autoimmune disorders.
6.Patient underwent blood transfusion for < 1 week
7.Patients not willing to give consent
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Difference in biochemical and hematological markers (complete blood count, IL-6) at three time points (preoperatively, immediately and 24hours after the end of the surgery) in COVID positive/suspect patients undergoing major surgeryTimepoint: Baseline <br/ ><br>At end of surgery <br/ ><br>24 hours post surgery
- Secondary Outcome Measures
Name Time Method Early mortality- within same hospital admission/within one month, whichever is earlierTimepoint: one month;Major morbidity- Surgical site infection, Need for post-operative ventilation and its duration, need for BIPAP support, Duration of ventilation, inotropic score, ICU stay, length of hospital stayTimepoint: peri-operative;Perioperative adverse events- hypotension, hypoxia, apnea, bradycardia and cardiac arrest.Timepoint: Perioperative