can the change in size of large blood vessel in stomach during transiently increasing breath volume predict the response to fluid therapy in seriously ill patients on mechanical ventilator?
Not Applicable
- Conditions
- Health Condition 1: J80- Acute respiratory distress syndromeHealth Condition 2: B972- Coronavirus as the cause of diseases classified elsewhereHealth Condition 3: I959- Hypotension, unspecifiedHealth Condition 4: R098- Other specified symptoms and signsinvolving the circulatory and respiratory systemsHealth Condition 5: J189- Pneumonia, unspecified organismHealth Condition 6: J99- Respiratory disorders in diseasesclassified elsewhere
- Registration Number
- CTRI/2021/09/036633
- Lead Sponsor
- atesh Prabu R
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Adult patients (Age > 18 yrs )
Acute circulatory failure
Receiving protective lung ventilation <= 6ml/kg IBW using Volume Assist Control mode, without any spontaneous activity
Need of prone ventilation as decided by treating physician.
Exclusion Criteria
Acute myocardial infarction
Previously known significant valvular disease or intracardiac shunt
Air leakage through chest drains
Right heart failure
An urgently required fluid challenge.
Abdominal compartment syndrome, and pregnancy
Raised intracranial hypertension
Recent Abdominal surgery
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine whether the change inâ?¯Inferior Vena Cava distensibility indexâ?¯â?¯inâ?¯lateral approachâ?¯during â??tidal volume challengeâ?? can reliably predict fluid responsiveness in patients ventilated in prone positionâ?¯â?¯Timepoint: at baseline
- Secondary Outcome Measures
Name Time Method To determine whether Inferior Vena Cava -Distensibility index in lateral approach has good correlation and agreement during tidal volume challengeâ?¯in supine and prone positionsTimepoint: immediate;To determine whether Inferior Vena Cava distensibility indexâ?¯inâ?¯subxiphoidâ?¯and lateral approach has good correlation andâ?¯agreement during tidal volume challengeTimepoint: baseline