Whether transiently increasing breath volume and measuring variability in blood pressure and variability in size of major blood vessel in abdomen in pts receiving low breath volume from breathing machine who has poor lung functions would help in predicting the response to fluid therapy?
Not Applicable
- Conditions
- Health Condition 1: null- Pt with Acute circulatory failure and Receiving protective lung ventilation less than or equal to 6ml/kg using Volume control mode without any spontaneous activity and with cardiac output monitoring
- Registration Number
- CTRI/2017/04/008378
- Lead Sponsor
- Dept of Anaesthesia Critical care and Pain
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 26
Inclusion Criteria
1.Adult patients (Age > 18 yrs )
2.Acute circulatory failure
3.Receiving protective lung ventilation <= 6ml/kg IBW using Volume Assist Control mode, without any spontaneous activity
4.With cardiac output monitoring using Flotrac/Volume View with Phillips Intel View monitor (MP700)
5.Treating physician has decided to give fluid bolus
Exclusion Criteria
1.Cardiac arrhythmias, Acute myocardial infarction
2.Previously known significant valvular disease or intracardiac shunt
3.Air leakage through chest drains
4.Right heart failure
5.An urgently required fluid challenge
6.Abdominal compartment syndrome, and pregnancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine whether the â??tidal volume challengeâ?? can improve the reliability of PPV and SVV in predicting fluid responsiveness in patients having low lung compliance ventilated using low Vt ventilationTimepoint: before and after giving fluid therapy
- Secondary Outcome Measures
Name Time Method 1.To determine whether IVC-DI can reliably predict fluid responsiveness in patients receiving low Vt ventilation <br/ ><br>2.To determine whether the â??tidal volume challengeâ?? can improve the reliability of IVC-DI in predicting fluid responsiveness in patients receiving low Vt ventilation <br/ ><br>Timepoint: before and after giving fluid therapy