A clinical study to evaluate the fluid response in patients undergoing neurosurgery.
Not Applicable
- Conditions
- Health Condition 1: G998- Other specified disorders of nervous system in diseases classified elsewhere
- Registration Number
- CTRI/2023/08/056880
- Lead Sponsor
- AIIMS New delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All elective neurosurgical patients (age >18 years, ASA I II) requiring sitting positioning will be considered eligible.
Exclusion Criteria
o Any recurrent cardiac arrhythmia; reduced ventricular systolic function - left (ejection fraction <40%),
o BMI more than 30
o Intra-operative use of vasopressors or inotropes before or during TVC
o Chronic lung disease
o Pre-operative use of beta blocking agents.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the reliability of changes in pulse pressure variation (PPV) & stroke volume variation (SVV) values induced by tidal volume challenge in predicting fluid responsiveness in patients undergoing neurosurgery in the sitting position under 6 ml/kg (PBW)Timepoint: To assess the reliability of changes in pulse pressure variation (PPV) & stroke volume variation (SVV) values induced by tidal volume challenge in predicting fluid responsiveness in patients undergoing neurosurgery in the sitting position under 6 ml/kg (PBW)
- Secondary Outcome Measures
Name Time Method To assess the reliability of pulse pressure variation (PPV) & stroke volume variation (SVV) at 6 ml/kg & 8 ml/kg.Timepoint: Starting point - At the point when sitting postion of the patint is achieved with hemodynamic stability. <br/ ><br> <br/ ><br>End Point - At the point when Hemodynamic parameters are noted after the fluid challenge.