Can transiently raising breath volume to higher (normal) breath volume in patients on ventilator receiving low breath volume and by measuring blood pressure change will help to identify patients who will get benefited from giving fluids.
Not Applicable
- Conditions
- Health Condition 1: null- Patients Age18yrsAcute circulatory failure Deeply sedated/paralysed)With invasive cardiac output monitoring using PICCO/ Volume View
- Registration Number
- CTRI/2015/11/006335
- Lead Sponsor
- Dr Sheila Nainan Myatra
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
•Adult patients (Age > 18 yrs )
•Acute circulatory failure
•Receiving protective lung ventilation <= 6ml/kg IBW using Volume Assist Control mode, without any spontaneous activity (deeply sedated/paralysed)
•With invasive cardiac output monitoring using PICCO/ Volume View with Phillips Intel View monitor (MP700)
Exclusion Criteria
•Cardiac arrhythmias, IHD
•Previously known significant valvular disease or intracardiac shunt
•Air leakage through chest drains
•An urgently required fluid challenge
•Abdominal compartment syndrome, and pregnancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To detect whether measuring PPV by transiently increasing tidal volume to 8ml/kg IBW in patients ventilated with low tidal volume, can reliably predict fluid responsiveness.Timepoint: 1 year
- Secondary Outcome Measures
Name Time Method To detect whether EEOT is reliable in patients ventilated with 6 ml/kg IBW.Timepoint: 1 year