Hypercapnia During Shoulder Arthroscopy

Not Applicable

Completed

• Conditions: Cerebral Ischemia
• Interventions: Behavioral: normocapnia; Behavioral: hypercapnia

• Registration Number: NCT02643030
• Lead Sponsor: Gachon University Gil Medical Center

Brief Summary

The purpose of this study is to evaluate the effects of hypercapnia on hemodynamics and cerebral oxygenation during shoulder arthroscopy.

Detailed Description

The patients are randomly allocated to receive normocapnia or hypercapnia . After the 70º sitting position, record the mean arterial pressure (MAP), heart rate, and regional oxygen saturation (rSO2).

Study Timeline

• Study Start: 2012-03
• Primary Completion: 2015-09
• Study Completion: 2015-10
• Status Verified: 2015-12
• Study First Submitted: 2015-12-23
• Study First Submitted QC: 2015-12-28
• Last Update Submitted: 2015-12-28
• Study First Posted: 2015-12-30
• Last Update Posted: 2015-12-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• patients undergoing elective shoulder arthroscopic surgery

Exclusion Criteria

• a history of age > 65 years, morbidly obesity (BMI > 30 kg/m2), diffuse lung disease, uncontrolled systemic hypertension, intracranial disease, cardiovascular and cerebrovascular disease.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
normocapnia	normocapnia	Tidal volume (10 ml/kg) and respiratory rate is adjusted to achieve the objective values of ETCO2 35mmHg
hypercapnia	hypercapnia	Tidal volume (6ml/kg) and respiratory rate is adjusted to achieve the objective values of ETCO2 45mmHg

Primary Outcome Measures

Name	Time	Method
Regional cerebral oxygen saturation	Change from Regional cerebral oxygen saturation at 2,4,6,8,10,20 min after anesthetic induction and sitting position