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Safety Study of Oral Azacitidine (CC-486) as Maintenance Therapy After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in Participants With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndromes (MDS).

Phase 1
Completed
Conditions
Leukemia, Myeloid, Acute
Myelodysplastic Syndromes
Interventions
First Posted Date
2013-04-19
Last Posted Date
2018-11-20
Lead Sponsor
Celgene
Target Recruit Count
31
Registration Number
NCT01835587
Locations
🇺🇸

Memorial Sloan-Kettering Cancer Center., New York, New York, United States

🇺🇸

University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States

🇺🇸

MD Anderson Cancer Center The University of Texas, Houston, Texas, United States

and more 2 locations

Phase II Study of Decitabine and Cytarabine for Older Patients With Newly Diagnosed Acute Myeloid Leukemia (AML)

Phase 2
Completed
Conditions
Acute Myeloid Leukemia
Interventions
Other: Supportive Care
First Posted Date
2013-04-11
Last Posted Date
2019-11-14
Lead Sponsor
Annie Im, M.D.
Target Recruit Count
44
Registration Number
NCT01829503
Locations
🇺🇸

University of PIttsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States

Respiratory Viral Infections During Acute Myeloid Leukemia (AML)Chemotherapy Related Aplasia

Phase 4
Completed
Conditions
Acute Myeloid Leukemia
First Posted Date
2013-03-28
Last Posted Date
2018-04-23
Lead Sponsor
Centre Hospitalier Universitaire, Amiens
Target Recruit Count
119
Registration Number
NCT01819792
Locations
🇫🇷

Pr Marolleau, Amiens, France

🇫🇷

CHU CAEN, Caen, France

🇫🇷

Chru Lille, Lille, France

and more 1 locations

Transplantation of NiCord®, Umbilical Cord Blood-derived Ex Vivo Expanded Cells, in Patients With HM

Phase 1
Completed
Conditions
Hematological Malignancies
Acute Lymphoblastic Leukemia (ALL)
Myelodysplastic Syndrome (MDS)
Acute Myeloid Leukemia (AML)
Interventions
First Posted Date
2013-03-22
Last Posted Date
2020-10-22
Lead Sponsor
Gamida Cell ltd
Target Recruit Count
36
Registration Number
NCT01816230
Locations
🇺🇸

Cedars-Sinai Medical Center, Los Angeles, California, United States

🇺🇸

Loyola University, Cardinal Bernardin Cancer Center, Maywood, Illinois, United States

🇺🇸

University of Minnesota, Minneapolis, Minnesota, United States

and more 12 locations

Decitabine for Older or Unfit Patients With Acute Myeloid Leukemia (AML)

Phase 2
Completed
Conditions
Leukemia
Interventions
First Posted Date
2013-02-07
Last Posted Date
2020-04-15
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
74
Registration Number
NCT01786343
Locations
🇺🇸

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

Treosulfan/Fludarabine/Low Dose TBI as a Preparative Regimen for Children With AML/MDS Undergoing Allo HCT

Phase 2
Completed
Conditions
Acute Myeloid Leukemia (AML)
Myelodysplastic Syndrome (MDS)
Interventions
First Posted Date
2013-01-21
Last Posted Date
2016-10-12
Lead Sponsor
Center for International Blood and Marrow Transplant Research
Target Recruit Count
40
Registration Number
NCT01772953
Locations
🇺🇸

Children's Hospital of Alabama/UAB, Birmingham, Alabama, United States

🇺🇸

Phoenix Children's Hospital, Phoenix, Arizona, United States

🇺🇸

City of Hope, Duarte, California, United States

and more 20 locations

Maintenance Therapy With Histamine Dihydrochloride and Interleukin-2 in Adult Acute Myeloid Leukemia (AML) Patients With Measurable Minimal Residual Disease (MRD)- a Non-interventional Study (NIS)

Terminated
Conditions
Acute Myeloid Leukemia
First Posted Date
2013-01-17
Last Posted Date
2018-04-09
Lead Sponsor
University of Ulm
Target Recruit Count
8
Registration Number
NCT01770158
Locations
🇩🇪

Vivantes Hospital Neukölln, Berlin, Germany

🇩🇪

Charite, University Medical School of Berlin, Berlin, Germany

🇩🇪

Darmstadt Clinic, Darmstadt, Germany

and more 19 locations

Efficacy of Oral Azacitidine Plus Best Supportive Care as Maintenance Therapy in Subjects With Acute Myeloid Leukemia (AML) in Complete Remission

Phase 3
Completed
Conditions
Leukemia, Myeloid, Acute
Interventions
First Posted Date
2012-12-31
Last Posted Date
2025-07-08
Lead Sponsor
Celgene
Target Recruit Count
472
Registration Number
NCT01757535
Locations
🇺🇸

Arizona Oncology Associates, P.C., Phoenix, Arizona, United States

🇺🇸

Providence St Joseph Medical Center Cancer Center, Burbank, California, United States

🇺🇸

City Of Hope, Duarte, California, United States

and more 220 locations

Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders

Not Applicable
Recruiting
Conditions
Chronic Kidney Disease
Multiple Myeloma
Acute Myeloid Leukemia (AML)
Chronic Myelogenous Leukemia (CML)
Aplastic Anemia
AL Amyloidosis
Chronic Lymphocytic Leukemia (CLL)
Non-Hodgkin's Lymphoma (NHL)
Myelodysplastic Syndrome (MDS)
Myelofibrosis
First Posted Date
2012-12-31
Last Posted Date
2023-03-15
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
10
Registration Number
NCT01758042
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

Assessment of Body, Liver and Labile Plasma Iron and Their Association With Outcome and Immunological Recovery in Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML) Patients Undergoing Allogeneic Stem Cell Transplantation - ALLIVE (ALLogeneic Iron inVEstigators) Observational Trial

Completed
Conditions
MDS and AML Prior to Allogeneic SCT
First Posted Date
2012-12-10
Last Posted Date
2016-12-13
Lead Sponsor
GWT-TUD GmbH
Target Recruit Count
134
Registration Number
NCT01746147
Locations
🇩🇪

III. Medizinischen Klinik Hämatologie und Internistische Onkologie Universitätsmedizin Mannheim, Mannheim, Baden-Württemberg, Germany

🇩🇪

III. Medizinischen Klinik des Klinikums rechts der Isar, München, Bayern, Germany

🇩🇪

Universitätsklinikum MKII, Hämatologie/Onkologie, Universitäres Zentrum für Tumorerkrankungen, Frankfurt, Hessen, Germany

and more 2 locations

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