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Relative Bioavailability of Tiotropium and Salmeterol After Inhalation of a Fixed Combined Dose Compared to Monocomponents in Healthy Male Volunteers

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: Tiotropium/Salmeterol
First Posted Date
2014-10-01
Last Posted Date
2014-10-01
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
36
Registration Number
NCT02254174

Multiple Rising Dose of BI 1181181 Given Orally in Young Healthy Male and Elderly Healthy Male/Female Volunteers

Phase 1
Terminated
Conditions
Healthy
Interventions
Drug: Matching placebo
Drug: BI 1181181 Healthy young
Drug: BI 1181181 healthy elderly
First Posted Date
2014-10-01
Last Posted Date
2018-08-31
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
36
Registration Number
NCT02254161
Locations
🇩🇪

1344.2.1 Boehringer Ingelheim Investigational Site, Berlin, Germany

Effects of Steady State Tipranavir/Ritonavir or Darunavir/Ritonavir or Ritonavir on Platelet Function, Coagulation and Fibrinolysis Biomarkers in Healthy Subjects

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2014-09-29
Last Posted Date
2014-09-29
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
52
Registration Number
NCT02251795

Evaluation of the Pharmacokinetic Interaction of Steady State Tipranavir and Ritonavir or Tipranavir and Ritonavir With Single Dose Didanosine in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: TPV + RTV (low dose)
Drug: TPV + RTV (high dose)
Drug: ddl
First Posted Date
2014-09-29
Last Posted Date
2014-09-29
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
50
Registration Number
NCT02251873

Pharmacokinetics of Tipranavir Soft Elastic Capsules (SEDDS) and Ritonavir and Their Effects on Cytochrome P-450 (3A4) in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: TPV low 2
Drug: TPV medium
Drug: TPV high 1
Drug: TPV low 1
Drug: TPV high 2
First Posted Date
2014-09-29
Last Posted Date
2014-09-29
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
113
Registration Number
NCT02251132

The Pharmacodynamic/Pharmacokinetic Interaction of Tipranavir and Ritonavir With Loperamide in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2014-09-29
Last Posted Date
2014-09-29
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
24
Registration Number
NCT02251119
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