利福布汀 (Mycobutin, Talicia)

概览

Rifabutin is an antibiotic used to treat mycobacterium avium complex disease in patients with HIV.

作用机制

Rifabutin acts via the inhibition of DNA-dependent RNA polymerase in gram-positive and some gram-negative bacteria, leading to a suppression of RNA synthesis and cell death.

适应症

For the prevention of disseminated Mycobacterium avium complex (MAC) disease in patients with advanced HIV infection.

• Helicobacter Pylori Infection
• Mycobacterium avium complex infection
• Tuberculosis (TB)
• Late phase Tuberculosis