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A Clinical Study Investigating the Therapeutic Effects and Safety of an Investigational Cell Therapy Given With and Without an Additional Investigational Product in Males With Testicular Cancer or a Form of Cancer That Developed From Sperm
Phase 2
Not yet recruiting
- Conditions
- Testicular Germ Cell TumorExtragonadal Germ Cell Tumor
- Interventions
- Biological: CLDN6 CAR-T
- First Posted Date
- 2025-04-23
- Last Posted Date
- 2025-04-23
- Lead Sponsor
- BioNTech SE
- Target Recruit Count
- 150
- Registration Number
- NCT06940804
Sequential PEG-IFN for HBV After Ending RNA-targeted Regimens
Not Applicable
Not yet recruiting
- Conditions
- Hepatitis B, Chronic
- Interventions
- Drug: Pegylated Interferon-alpha (IFN)
- First Posted Date
- 2025-04-11
- Last Posted Date
- 2025-04-11
- Lead Sponsor
- Huashan Hospital
- Target Recruit Count
- 30
- Registration Number
- NCT06923280
- Locations
- 🇨🇳
Huashan Hospita, Shanghai, China
A Study to Evaluate the Safety and Immunogenicity of the V3-region Directed Immunogens DV700P-RNA Followed by DV701B1.1-RNA in Adults Without HIV
Phase 1
Not yet recruiting
- Conditions
- HIV-1-infection
- Interventions
- Biological: DV700P-RNABiological: DV701B1.1-RNA
- First Posted Date
- 2025-04-09
- Last Posted Date
- 2025-04-09
- Target Recruit Count
- 45
- Registration Number
- NCT06919016
- Locations
- 🇺🇸
University of Alabama Medical Center (Site ID: 31788), Birmingham, Alabama, United States
🇺🇸Hope Clinic (Site ID: 31440), Decatur, Georgia, United States
🇺🇸Columbia University Medical Center (Site ID: 10032), New York, New York, United States
RNA Assays for Endometriosis Detection and Diagnosis
- Conditions
- Endometriosis
- First Posted Date
- 2025-04-02
- Last Posted Date
- 2025-04-02
- Lead Sponsor
- Wren Laboratories LLC
- Target Recruit Count
- 400
- Registration Number
- NCT06907303
- Locations
- 🇺🇸
Wren Laboratories, Branford, Connecticut, United States
🇿🇦University of Cape Town, Cape Town, South Africa
Metagenomics Next-generation Sequencing Approach to Detect Microbial DNA/RNA Overtime in Individuals Undergoing Hematopoietic Stem Cell Transplant
Recruiting
- Conditions
- Hematopoietic Stem Cell Transplantation
- First Posted Date
- 2025-04-01
- Last Posted Date
- 2025-04-15
- Target Recruit Count
- 30
- Registration Number
- NCT06904053
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
Explore the Mechanisms Underlying Disease Resistance and Potential Primary Resistance Mechanism of Induction Therapy Lorlatinib in Resectable Non-small Cell Lung Cancer (NSCLC) Harboring ALK Positive Mutation Revealed by Single-cell RNA Sequencing and Spatial Transcriptomics
Phase 4
Not yet recruiting
- Conditions
- NSCLC
- Interventions
- Drug: lorlatinib plus chemotherapy
- First Posted Date
- 2025-03-25
- Last Posted Date
- 2025-03-25
- Lead Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
- Target Recruit Count
- 20
- Registration Number
- NCT06893354
Mi-RNA and COVID-19
Recruiting
- Conditions
- COVID-19
- First Posted Date
- 2025-03-18
- Last Posted Date
- 2025-03-18
- Target Recruit Count
- 49
- Registration Number
- NCT06881160
- Locations
- 🇮🇹
Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, RM, Italy
855303-RNA Biomarker Validation
- Conditions
- Fractures, Bone
- First Posted Date
- 2025-03-12
- Last Posted Date
- 2025-04-16
- Lead Sponsor
- University of Pennsylvania
- Target Recruit Count
- 110
- Registration Number
- NCT06872775
- Locations
- 🇺🇸
University of Pennsylvania, Philadelphia, Pennsylvania, United States
Heterogeneity of Oral Squamous Cell Carcinoma Analysis by Single Cell RNA Sequencing
Not Applicable
Not yet recruiting
- Conditions
- Oral Squamous Cell Carcinomas
- First Posted Date
- 2025-03-06
- Last Posted Date
- 2025-03-06
- Lead Sponsor
- Centre Leon Berard
- Target Recruit Count
- 50
- Registration Number
- NCT06861036
- Locations
- 🇫🇷
Centre Léon Bérard, Lyon, France
"Immunoregulation in Atherosclerosis: A Single-Cell RNA Sequencing Study"
Not yet recruiting
- Conditions
- Atherosclerosis of Coronary Artery
- First Posted Date
- 2025-03-06
- Last Posted Date
- 2025-03-11
- Lead Sponsor
- Hospital Israelita Albert Einstein
- Target Recruit Count
- 30
- Registration Number
- NCT06860295
- Locations
- 🇧🇷
Hospital Israelita Albert Einstein, São Paulo, SP, Brazil
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