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A Study To Learn About The Study Vaccine (Called Self-Amplifying Ribonucleic Acid (RNA)) For The Prevention of Influenza

Phase 1
Completed
Conditions
Influenza, Human
Interventions
Biological: PF-07836394 Influenza saRNA
Biological: PF-07836396 Influenza saRNA
Biological: PF-07852352 Influenza saRNA 1
Biological: PF-07836395 Influenza saRNA
Biological: PF-07867246 Influenza saRNA
Biological: PF-07915048 Influenza saRNA
Biological: PF-07836391 Influenza saRNA
Biological: PF-07871987 Influenza saRNA
Biological: PF-07914705 Influenza saRNA
Biological: Placebo
Biological: Quadrivalent influenza vaccine (QIV)
First Posted Date
2022-02-07
Last Posted Date
2023-09-11
Lead Sponsor
Pfizer
Target Recruit Count
442
Registration Number
NCT05227001
Locations
🇺🇸

Great Lakes Clinical Trials - Andersonville, Chicago, Illinois, United States

🇺🇸

Pioneer Heart Institute, Lincoln, Nebraska, United States

🇺🇸

Arizona Heart Rhythm Center, Phoenix, Arizona, United States

and more 22 locations

Assessing Safety of Coronavirus Infection (COVID-19) Messenger RNA (mRNA) Vaccine Administration in the Setting of a Previous Adverse Reaction

Phase 4
Completed
Conditions
COVID-19
Corona Virus Infection
Interventions
Biological: Pfizer-BioNTech mRNA COVID-19 vaccine
First Posted Date
2022-01-28
Last Posted Date
2025-04-17
Lead Sponsor
University of Michigan
Target Recruit Count
103
Registration Number
NCT05212610
Locations
🇺🇸

University of Michigan, Ann Arbor, Michigan, United States

A Study of RNA Tumor Vaccine in Patients With Advanced Solid Tumors

Phase 1
Conditions
Advanced Solid Tumor
Interventions
Biological: RNA tumor vaccine
Biological: RNA tumor vaccine+Navuliumab
First Posted Date
2022-01-21
Last Posted Date
2022-03-23
Lead Sponsor
First Affiliated Hospital Bengbu Medical College
Target Recruit Count
10
Registration Number
NCT05202561
Locations
🇨🇳

First Affiliated Hospital Bengbu Medical College, Bengbu, Anhui, China

Circulating EV Long RNA Profiles in SCLC

Not Applicable
Recruiting
Conditions
Small Cell Lung Cancer
Interventions
Diagnostic Test: Blood sample collection
First Posted Date
2022-01-14
Last Posted Date
2022-01-14
Lead Sponsor
Fudan University
Target Recruit Count
60
Registration Number
NCT05191849
Locations
🇨🇳

Cancer hospital Fudan University, Shanghai, Shanghai, China

Combining Exome and Transcriptome Data to Unravel the Genetic Basis of the Lissencephalies

Not Applicable
Not yet recruiting
Conditions
Classical Lissencephalies and Subcortical Band Heterotopias
Interventions
Diagnostic Test: Venipuncture and skin biopsy for RNA extraction
First Posted Date
2022-01-11
Last Posted Date
2022-01-11
Lead Sponsor
Universitair Ziekenhuis Brussel
Target Recruit Count
50
Registration Number
NCT05185414
Locations
🇧🇪

UZ Brussel, Jette, Brussel, Belgium

Discovering Early Biomarkers in Circulating Endothelial Cells for Diabetes Complications by Single Cell RNA Sequencing

Completed
Conditions
Diabetic Maculopathy
Diabetes
Diabetes Mellitus
Proliferative Diabetic Retinopathy
Circulating Endothelial Cells
First Posted Date
2021-12-27
Last Posted Date
2024-08-20
Lead Sponsor
Aarhus University Hospital
Target Recruit Count
40
Registration Number
NCT05169502
Locations
🇩🇰

Steno Diabetes Center Aarhus, Aarhus University Hospiral, Aarhus, Denmark

The WILLOW Study With M5049 in SLE and CLE (SCLE and/or DLE) (WILLOW)

Phase 2
Completed
Conditions
Systemic Lupus Erythematosus
Interventions
Drug: Enpatoran medium dose
Drug: Enpatoran high dose
Drug: Enpatoran low dose
Drug: Placebo
First Posted Date
2021-12-17
Last Posted Date
2024-12-05
Lead Sponsor
EMD Serono Research & Development Institute, Inc.
Target Recruit Count
456
Registration Number
NCT05162586
Locations
🇺🇸

The Lundquist Institute at Harbor-UCLA Medical Center, Torrance, California, United States

🇺🇸

Bay Area Arthritis and Osteoporosis, Brandon, Florida, United States

🇺🇸

Charisma Medical and Research Center, Miami Lakes, Florida, United States

and more 150 locations

TOlerance MOlecular and Genome-wide Studies With Renal Allograft Recipient Material

Not Applicable
Completed
Conditions
Kidney Transplantation
Interventions
Genetic: High throughput DNA and RNA sequencing
First Posted Date
2021-11-18
Last Posted Date
2021-11-18
Lead Sponsor
Université Libre de Bruxelles
Target Recruit Count
18
Registration Number
NCT05124444

Plasma SARS-CoV-2 RNA Levels in Critically Ill COVID-19 Patients

Completed
Conditions
ARDS Due to Disease Caused by Severe Acute Respiratory Syndrome Coronavirus 2
COVID-19 Pneumonia
First Posted Date
2021-11-10
Last Posted Date
2023-04-03
Lead Sponsor
Hopital of Melun
Target Recruit Count
122
Registration Number
NCT05115045
Locations
🇫🇷

Groupe Hospitalier Sud Ile de France, Hôpital de Melun-Sénart, Melun, France

Phase I Study of RNA Oligonucleotide, MTL-CEBPA, Atezolizumab and Bevacizumab in Patients With Advanced Hepatocellular Carcinoma.

Phase 1
Recruiting
Conditions
Advanced Hepatocellular Carcinoma
Interventions
First Posted Date
2021-10-28
Last Posted Date
2021-10-28
Lead Sponsor
National University Hospital, Singapore
Target Recruit Count
33
Registration Number
NCT05097911
Locations
🇸🇬

National University Hospital, Singapore, Singapore

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