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Diagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials: Early Test-of-cure

Not Applicable
Completed
Conditions
African; Trypanosomiasis, West
African Trypanosomiasis
Trypanosoma Brucei Gambiense; Infection
Sleeping Sickness; West African
Interventions
Diagnostic Test: RNA and neopterin detection
First Posted Date
2017-04-13
Last Posted Date
2021-02-21
Lead Sponsor
Institut de Recherche pour le Developpement
Target Recruit Count
88
Registration Number
NCT03112655
Locations
🇨🇩

Programme Nationale de Lutte contre la trypanosomiase humaine Africaine, Kinshasa, Congo, The Democratic Republic of the

VRC 705: A Zika Virus DNA Vaccine in Healthy Adults and Adolescents

Phase 2
Completed
Conditions
Zika Virus Infection
Flaviviral Diseases
Virus Diseases
RNA Virus Infections
Zika Virus
Flavivirus Infections
Flaviviridae Infections
Interventions
Biological: VRC-ZKADNA090-00-VP
Other: VRC-PBSPLA043-00-VP
First Posted Date
2017-04-12
Last Posted Date
2024-01-31
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
2428
Registration Number
NCT03110770
Locations
🇵🇦

Instituto Conmemorativo Gorgas, Panamá, San Miguelito Province, Panama

🇵🇷

Puerto Rico Clinical and Translational Research Consortium, San Juan, Puerto Rico

🇨🇴

Clinica de la Costa Ltda, Barranquilla, Atlantico, Colombia

and more 14 locations

Circulating Exosome RNA in Lung Metastases of Primary High-Grade Osteosarcoma

Active, not recruiting
Conditions
Lung Metastases
Osteosarcoma
Interventions
Other: Blood samples
First Posted Date
2017-04-11
Last Posted Date
2023-10-03
Lead Sponsor
Ruijin Hospital
Target Recruit Count
90
Registration Number
NCT03108677
Locations
🇨🇳

Ruijin Hospital Shanghai Jiao Tong University School of medicine, Shanghai, Shanghai, China

PREVAIL VI: Identification of Host Genetic Factors Underlying Ebola Virus Disease Risk, Mortality, Long-term Sequelae, Viral RNA Persistence, Humoral Immunity, and Ebola Vaccine Response

Completed
Conditions
Ebola Virus Disease
First Posted Date
2017-04-04
Last Posted Date
2022-08-22
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
4830
Registration Number
NCT03098862
Locations
🇱🇷

PREVAIL C. H. Rennie Hospital, Kalkata, Liberia

🇱🇷

PREVAIL JFK Medical Center, Monrovia, Liberia

🇱🇷

PREVAIL Duport Road Clinic, Paynesville, Liberia

and more 1 locations

Molecular Characterization of Cutaneous Tumors

Conditions
Squamous Cell Carcinoma
Basal Cell Carcinoma
Interventions
Genetic: Molecular testing of DNA/RNA from skin tumors, SCC/BCC
First Posted Date
2017-03-28
Last Posted Date
2019-04-30
Lead Sponsor
Rabin Medical Center
Target Recruit Count
500
Registration Number
NCT03092830
Locations
🇮🇱

RabinMC, Petach Tikva, Israel

Autologous T Cells Expressing MET scFv CAR (RNA CART-cMET)

Early Phase 1
Terminated
Conditions
Malignant Melanoma
Breast Cancer
Interventions
Biological: T cells modified with RNA anti -cMET CAR
First Posted Date
2017-02-23
Last Posted Date
2023-06-22
Lead Sponsor
University of Pennsylvania
Target Recruit Count
77
Registration Number
NCT03060356
Locations
🇺🇸

University of Pennsylvania, Philadelphia, Pennsylvania, United States

A Study on the Gastrointestinal Disease and Helicobacter Pylori Controlled Long Non-coding RNA

Conditions
Stomach Cancer
Helicobacter Pylori Infection
Gastric Ulcer
Duodenal Ulcer
First Posted Date
2017-02-17
Last Posted Date
2019-03-18
Lead Sponsor
Yonsei University
Target Recruit Count
50
Registration Number
NCT03057171
Locations
🇰🇷

Yonsei university College of Medicine, Seoul, Korea, Republic of

Pathogenic Mechanisms of Cancer and Cardiovascular Diseases

Completed
Conditions
Cancer
Pathogenesis
Cardiovascular Diseases
Interventions
Diagnostic Test: micro RNA
First Posted Date
2017-02-13
Last Posted Date
2020-10-22
Lead Sponsor
Sakakibara Heart Institute
Target Recruit Count
66
Registration Number
NCT03051191
Locations
🇯🇵

The Cancer Institute Hospital for Japanese Foundation for Cancer Research, Tokyo, Japan

🇯🇵

Sakakibara Heart Institute, Fuchu, Japan

Biomarkers to Predict Time to Plasma HIV RNA Rebound

Completed
Conditions
HIV-1 Infection
Interventions
Drug: Antiretroviral treatment pause
First Posted Date
2016-12-22
Last Posted Date
2024-12-13
Lead Sponsor
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Target Recruit Count
61
Registration Number
NCT03001128
Locations
🇺🇸

601 University of California, Los Angeles CARE Center CRS, Los Angeles, California, United States

🇺🇸

701 University of California, San Diego AntiViral Research Center CRS, San Diego, California, United States

🇺🇸

801 University of California, San Francisco HIV/AIDS CRS, San Francisco, California, United States

and more 15 locations

RNA and Heat Shock Protein Biomarkers in Radiation-induced Fibrosis in Breast Cancer

Not Applicable
Completed
Conditions
Breast Carcinoma
Fibrosis
Interventions
Other: skin biopsies
Other: blood samples
First Posted Date
2016-12-22
Last Posted Date
2018-08-08
Lead Sponsor
Institut de Cancérologie de Lorraine
Target Recruit Count
20
Registration Number
NCT03000764
Locations
🇫🇷

Institut de Cancérologie de Lorraine, Vandœuvre-lès-Nancy, France

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