An Open-label, Multicenter Phase Ib/II Clinical Study to Evaluate the Safety, Efficacy, and Pharmacokinetic of PLB1004 Capsules Combined With Platinum-based Doublet Chemotherapy in Patients With EGFR Mutation Positive Non-small Cell Lung Cancer (NSCLC)
- Conditions
- NSCLC (Non-small Cell Lung Cancer)
- Interventions
- Drug: PLB1004 80mg/160mg/240mg oral once daily Combined with Platinum-Based ChemotherapyDrug: RP2D of PLB1004 oral once daily Combined with Platinum-Based Chemotherapy
- First Posted Date
- 2025-07-14
- Last Posted Date
- 2025-07-14
- Lead Sponsor
- Avistone Pharmaceutical(Ningbo)Co., LTD.
- Target Recruit Count
- 108
- Registration Number
- NCT07063329
- Locations
- 🇨🇳
Shanghai Chest hospital, Shanghai, Shanghai, China
The Effect of Laughter Yoga on Spiritual Care Perception and Spiritual Well Being in Nursing Students
- Conditions
- SpiritualitySpiritual Well-beingLaughter Yoga
- First Posted Date
- 2025-07-14
- Last Posted Date
- 2025-07-14
- Lead Sponsor
- Izmir Democracy University
- Target Recruit Count
- 60
- Registration Number
- NCT07062029
- Locations
- 🇹🇷
Izmir Democracy University, Izmir, Konak, Turkey
Psilocybin Microdose for Psychological and Existential Distress in Palliative Care (PSYCHED-PAL-RCT)
- Conditions
- Psychological Distress
- Interventions
- Drug: Placebo
- First Posted Date
- 2025-07-14
- Last Posted Date
- 2025-07-14
- Lead Sponsor
- Bruyère Health Research Institute.
- Target Recruit Count
- 120
- Registration Number
- NCT07063862
- Locations
- 🇨🇦
William Osler Health System, Brampton, Ontario, Canada
🇨🇦Providence Care Hospital, Kingston, Ontario, Canada
🇨🇦St. Joseph's Healthcare, London, Ontario, Canada
Er,Cr:YSGG Laser for Deepithelialization in Gingival Recession.
- Conditions
- Gingival Recession, LocalizedKeratinized TissueGingival ThicknessPocket Depth
- First Posted Date
- 2025-07-14
- Last Posted Date
- 2025-07-14
- Lead Sponsor
- Wroclaw Medical University
- Target Recruit Count
- 9
- Registration Number
- NCT07064304
- Locations
- 🇵🇱
Dentoplex, Bielsko-Biala, Poland
Endoscopic Ultrasound-guided Measurement of Portal Vein Pressure Gradient
- Conditions
- Portal Vein ThrombosisPortal Hypertension Related to Cirrhosis
- First Posted Date
- 2025-07-14
- Last Posted Date
- 2025-07-14
- Lead Sponsor
- Zhejiang University
- Target Recruit Count
- 42
- Registration Number
- NCT07062289
Combined Effects of Bruegger's Exercises and Upper Thoracic Mobilizations in Patients With Non-specific Neck Pain
- Conditions
- Neck Pain
- First Posted Date
- 2025-07-14
- Last Posted Date
- 2025-07-14
- Lead Sponsor
- Riphah International University
- Target Recruit Count
- 48
- Registration Number
- NCT07063004
- Locations
- 🇵🇰
Medical and Rehabilitation Center, Gujrat, Gujrat, Punjab, Pakistan
Pelvic Floor Exercises for Suboptimal Anorectal Manometry
- Conditions
- Obstetric Anal Sphincter Injury
- First Posted Date
- 2025-07-14
- Last Posted Date
- 2025-07-14
- Lead Sponsor
- King's College Hospital NHS Trust
- Target Recruit Count
- 50
- Registration Number
- NCT07062731
- Locations
- 🇬🇧
Kings College Hospital, London, United Kingdom
Home-based EXercise and motivAtional Program Before and After Liver Transplantation
- Conditions
- Liver Transplant Surgery
- First Posted Date
- 2025-07-14
- Last Posted Date
- 2025-07-14
- Lead Sponsor
- University of Birmingham
- Target Recruit Count
- 269
- Registration Number
- NCT07063940
- Locations
- 🇬🇧
Birmingham Clinical Trials Unit (BCTU), Birmingham, United Kingdom
🇬🇧University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom
🇬🇧Royal Free Hospital, London, United Kingdom
Multimodal Deep Learning for Predicting Treatment Response to Neoadjuvant Chemoimmunotherapy in Esophageal Cancer
- Conditions
- Esophagus Cancer
- First Posted Date
- 2025-07-14
- Last Posted Date
- 2025-07-14
- Lead Sponsor
- Not specified
- Target Recruit Count
- 200
- Registration Number
- NCT07063901
- Locations
- 🇨🇳
The Second Xiangya Hospital of Central South University, Changsha, Hunan, China
The Role of Swan-Ganz Catheter in Hemodynamic Resuscitation for Patients With Cardiogenic Shock
- Conditions
- Cardiogenic ShockPulmonary Artery Catheter Waveform InterpretationHemodynamic ManagementHemodynamic OptimizationHemodynamic MonitoringAcute Myocardial Infarction (AMI)Critical Care, Intensive CareEmergencyCardio Vascular Disease
- First Posted Date
- 2025-07-14
- Last Posted Date
- 2025-07-14
- Lead Sponsor
- Bach Mai Hospital
- Target Recruit Count
- 108
- Registration Number
- NCT07062744
- Locations
- 🇻🇳
BachMai Hospital, Hanoi Medical University, Hanoi, Vietnam