Risperidone

Generic Name
Risperidone
Brand Names
Perseris, Risperdal, Rykindo, Uzedy, Okedi
Drug Type
Small Molecule
Chemical Formula
C23H27FN4O2
CAS Number
106266-06-2
Unique Ingredient Identifier
L6UH7ZF8HC
Background

Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions including schizophrenia and bipolar disorder. It is one of the most widely used SGAs. Paliperidone, another commonly used SGA, is the primary active metabolite of risperidone (i.e. 9-hydroxyrisperidone).
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Indication

Risperidone is indicated for the treatment of schizophrenia and irritability associated with autistic disorder. It is also indicated as monotherapy, or adjunctly with lithium or valproic acid, for the treatment of acute mania or mixed episodes associated with bipolar I disorder.
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Associated Conditions
Acute Mania, Irritability, Mixed manic depressive episode, Psychosis, Schizophrenia, Acute Manic episode, Agitated psychotic state
Associated Therapies
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Aripiprazole in the Treatment of Acutely Relapsed Patients With Schizophrenia

Phase 3
Completed
Conditions
First Posted Date
2006-01-27
Last Posted Date
2008-05-15
Lead Sponsor
Taiwan Otsuka Pharm. Co., Ltd
Target Recruit Count
83
Registration Number
NCT00283179
Locations
🇨🇳

National Taiwan University Hospital, Taipei, Taiwan

Study of Risperidone Monotherapy in Ambulatory Bipolar Disorder With Concurrent Moderately Severe Anxiety and Lifetime Panic or Generalized Anxiety Disorder

Phase 3
Completed
Conditions
Interventions
First Posted Date
2006-01-16
Last Posted Date
2011-12-13
Lead Sponsor
Lindner Center of HOPE
Target Recruit Count
111
Registration Number
NCT00277654
Locations
🇺🇸

University of Cincinnati Medical Center, Cincinnati, Ohio, United States

CARE Study: Improving Treatment for the Most Severely Ill With Schizophrenia

Phase 4
Completed
Conditions
First Posted Date
2006-01-06
Last Posted Date
2006-05-08
Lead Sponsor
University of British Columbia
Target Recruit Count
100
Registration Number
NCT00272584
Locations
🇨🇦

UBC Hospital, Vancouver, British Columbia, Canada

Risperidone LA Heathcare Resource Study

Phase 4
Completed
Conditions
Interventions
First Posted Date
2006-01-06
Last Posted Date
2017-11-29
Lead Sponsor
University of British Columbia
Target Recruit Count
30
Registration Number
NCT00272597
Locations
🇨🇦

Riverview Hospital, Coquitlam, British Columbia, Canada

SPECT Study With SB-773812 In Schizophrenic Patients

Phase 1
Completed
Conditions
Interventions
First Posted Date
2005-12-23
Last Posted Date
2017-08-17
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
95
Registration Number
NCT00269035
Locations
🇪🇸

GSK Investigational Site, Vic (Barcelona), Spain

Movement Disorders Caused by Antipsychotic Drugs in Older Patients

Phase 1
Completed
Conditions
First Posted Date
2005-11-21
Last Posted Date
2013-06-06
Lead Sponsor
University of California, San Diego
Target Recruit Count
250
Registration Number
NCT00255879
Locations
🇺🇸

University of California, San Diego Division of Geriatric Psychiatry, San Diego, California, United States

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