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Taurine

Generic Name
Taurine
Brand Names
Aminosyn-PF 7%, Premasol, Primene, Trophamine 10 %
Drug Type
Small Molecule
Chemical Formula
C2H7NO3S
CAS Number
107-35-7
Unique Ingredient Identifier
1EQV5MLY3D
Background

Taurine, whose chemical name is 2-aminoethanesulfonic acid, is one of the most abundant amino acids in several organs. It plays important role in essential biological processes. This conditional amino acid can be either be manufactured by the body or obtained in the diet mainly by the consumption of fish and meat. The supplements containing taurine were FDA approved by 1984 and they are hypertonic injections composed by cristalline amino acids.

Indication

The use of diet supplements containing taurine is indicated for the nutritional support of infants and young pediatric patients requiring total parenteral nutrition via central or peripheral routes. The usage of diet supplements containing taurine prevents nitrogen and weight loss or to treat negative nitrogen balance in pediatric patients where the alimentary tract cannot be done through oral, gastrostomy or jejunostomy administration, there is impaired gastrointestinal absorption or protein requirements are substantially increased.

Associated Therapies
Total parenteral nutrition therapy

Taurine Supplementation in Long COVID

Phase 2
Not yet recruiting
Conditions
Long COVID
Interventions
Drug: Placebo
First Posted Date
2024-12-06
Last Posted Date
2025-03-07
Lead Sponsor
University of Alberta
Target Recruit Count
300
Registration Number
NCT06721949
Locations
🇨🇦

University of Alberta Hospital, Kaye Edmonton Clinic, Edmonton, Alberta, Canada

Taurine Eye Drops May Prevent the Progression of Cataract

Phase 1
Active, not recruiting
Conditions
Cataract
Interventions
First Posted Date
2024-10-15
Last Posted Date
2024-12-09
Lead Sponsor
University Of Anbar
Target Recruit Count
50
Registration Number
NCT06639711
Locations
🇮🇶

Al-Nahrain Eye Clinics, Ramadi, Anbar, Iraq

Taurine Effect on Glycemic, Lipidic and Inflammatory Profile in Individuals with Type 2 Diabetes

Phase 2
Recruiting
Conditions
Diabetes Mellitus, Type 2
Interventions
Other: Placebo Comparator
First Posted Date
2021-05-05
Last Posted Date
2024-10-08
Lead Sponsor
Hospital de Clinicas de Porto Alegre
Target Recruit Count
94
Registration Number
NCT04874012
Locations
🇧🇷

Hospital de Clínicas, Porto Alegre, Rio Grande do Sul, Brazil

Effect of Amnion Membrane With and Without Taurine on GCF TNF α Level.

Not Applicable
Completed
Conditions
Periodontitis
Interventions
Procedure: Scaling and root planing
Biological: Amnion membrane
First Posted Date
2021-02-26
Last Posted Date
2021-03-16
Lead Sponsor
Maharishi Markendeswar University (Deemed to be University)
Target Recruit Count
45
Registration Number
NCT04772508
Locations
🇮🇳

Department of Periodontology, M.M. College of Dental Sciences and Research., Ambala, Haryana, India

Taurine in Peripartum Cardiomyopathy

Phase 2
Completed
Conditions
Peripartum Cardiomyopathy
Interventions
Dietary Supplement: Normal Saline
First Posted Date
2019-04-08
Last Posted Date
2020-01-28
Lead Sponsor
Ain Shams University
Target Recruit Count
40
Registration Number
NCT03907267
Locations
🇪🇬

Ain Shams University Maternity Hospital, Cairo, Egypt

Taurine Supplementation on Lower Extremity Vasculopathy in Patients With Diabetes

Not Applicable
Conditions
Taurine
Diabetes
Lower Extremity Artery Disease
Interventions
Drug: Placebo
First Posted Date
2018-01-25
Last Posted Date
2018-01-25
Lead Sponsor
Third Military Medical University
Target Recruit Count
200
Registration Number
NCT03410537
Locations
🇨🇳

The third hospital affiliated to the Third Military Medical University, Chongqing, Chongqing, China

Taurine Supplementation on Cognitive Function in Patients With Diabetes

Not Applicable
Conditions
Cognitive Decline
Diabetes Mellitus
Taurine
Interventions
Drug: Placebo
First Posted Date
2018-01-25
Last Posted Date
2018-01-25
Lead Sponsor
Third Military Medical University
Target Recruit Count
200
Registration Number
NCT03410173
Locations
🇨🇳

The third hospital affiliated to the Third Military Medical University, Chongqing, Chongqing, China

Impact of Energy Drinks on the Manual Dexterity of Final Year Dental Students

Phase 4
Completed
Conditions
Hand Skill, Relative
Interventions
Other: Test Cavity Preparation
Other: Post intervention test cavity
Dietary Supplement: Carbonated Apple Juice
First Posted Date
2015-08-28
Last Posted Date
2016-10-12
Lead Sponsor
Riyadh Colleges of Dentistry and Pharmacy
Target Recruit Count
60
Registration Number
NCT02535143
Locations
🇸🇦

Riyadh Colleges of Dentistry and Pharmacy, Riyadh, Saudi Arabia

Effects and Safety of Taurine Granule on Blood Pressure in Prehypertensive

Phase 3
Completed
Conditions
Prehypertension
Interventions
First Posted Date
2013-03-22
Last Posted Date
2015-11-24
Lead Sponsor
Zhiming Zhu
Target Recruit Count
120
Registration Number
NCT01816698
Locations
🇨🇳

The third hospital affiliated to the Third Military Medical University, Chongqing, Chongqing, China

Effect of Taurine on Glycemic Control in Type I and Type II Diabetic Patients

Phase 1
Conditions
it is a Group of Metabolic Diseases in
Which a Person Has High Blood Sugar, Either
Because the Body Does Not Produce Enough Insulin,
or Because Cells do Not Respond to the Insulin That
is Produced.
Interventions
First Posted Date
2010-10-22
Last Posted Date
2012-11-09
Lead Sponsor
Hamad Medical Corporation
Target Recruit Count
20
Registration Number
NCT01226537
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