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Taurine

Generic Name
Taurine
Brand Names
Aminosyn-PF 7%, Premasol, Primene, Trophamine 10 %
Drug Type
Small Molecule
Chemical Formula
C2H7NO3S
CAS Number
107-35-7
Unique Ingredient Identifier
1EQV5MLY3D
Background

Taurine, whose chemical name is 2-aminoethanesulfonic acid, is one of the most abundant amino acids in several organs. It plays important role in essential biological processes. This conditional amino acid can be either be manufactured by the body or obtained in the diet mainly by the consumption of fish and meat. The supplements containing taurine were FDA approved by 1984 and they are hypertonic injections composed by cristalline amino acids.

Indication

The use of diet supplements containing taurine is indicated for the nutritional support of infants and young pediatric patients requiring total parenteral nutrition via central or peripheral routes. The usage of diet supplements containing taurine prevents nitrogen and weight loss or to treat negative nitrogen balance in pediatric patients where the alimentary tract cannot be done through oral, gastrostomy or jejunostomy administration, there is impaired gastrointestinal absorption or protein requirements are substantially increased.

Associated Therapies
Total parenteral nutrition therapy

Oxidative Stress Markers In Inherited Homocystinuria And The Impact Of Taurine

Phase 1
Completed
Conditions
Homocystinuria
Interventions
First Posted Date
2010-09-01
Last Posted Date
2018-07-09
Lead Sponsor
University of Colorado, Denver
Target Recruit Count
15
Registration Number
NCT01192828
Locations
🇺🇸

Duke University, Durham, North Carolina, United States

🇺🇸

Childrens Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

🇺🇸

University of Colorado, Aurora, Colorado, United States

and more 1 locations

A Study of Taurine in Patients With First-episode Psychosis Receiving Antipsychotic Treatment

Phase 2
Completed
Conditions
Psychotic Disorders
Interventions
First Posted Date
2007-01-11
Last Posted Date
2015-11-20
Lead Sponsor
Melbourne Health
Target Recruit Count
121
Registration Number
NCT00420823
Locations
🇦🇺

RAPPS programme, Southern Health, Melbourne, Victoria, Australia

🇦🇺

ORYGEN Youth Health, Melbourne, Victoria, Australia

Taurine in Adolescents With Bipolar Disorder

Phase 1
Terminated
Conditions
Bipolar Disorder
Interventions
First Posted Date
2006-10-23
Last Posted Date
2010-02-03
Lead Sponsor
Cambridge Health Alliance
Target Recruit Count
4
Registration Number
NCT00391001
Locations
🇺🇸

McLean Hospital, Belmont, Massachusetts, United States

🇺🇸

Cambridge Health Alliance Child & Adolescent Neuropsychiatric Research Program, Medford, Massachusetts, United States

Taurine as an Anti-Manic Agent: A Double-Blind, Placebo-Controlled Study

Phase 2
Completed
Conditions
Mania
Bipolar Disorder
Bipolar Depression
Interventions
First Posted Date
2005-09-22
Last Posted Date
2019-03-01
Lead Sponsor
Mclean Hospital
Target Recruit Count
60
Registration Number
NCT00217165
Locations
🇺🇸

McLean Hospital, Belmont, Massachusetts, United States

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