Levetiracetam
- Generic Name
- Levetiracetam
- Brand Names
- Elepsia, Keppra, Matever, Roweepra, Spritam, Levetiracetam Accord, Levetiracetam Teva, Levetiracetam Actavis, Levetiracetam ratiopharm, Levetiracetam Sun, Levetiracetam Actavis Group, Levetiracetam Hospira
- Drug Type
- Small Molecule
- Chemical Formula
- C8H14N2O2
- CAS Number
- 102767-28-2
- Unique Ingredient Identifier
- 44YRR34555
- Background
Levetiracetam is a drug within the pyrrolidine class that is used to treat various types of seizures stemming from epileptic disorders. It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs). Levetiracetam possesses a wide therapeutic index and little-to-no potential t...
- Indication
Levetiracetam is indicated as an adjunctive therapy in the treatment of partial onset seizures in epileptic patients who are one month of age and older. Additionally, it is indicated as an adjunct in the treatment of myoclonic seizures in patients with juvenile myoclonic epilepsy who are 12 years of age and older, and in primary generalized tonic-clonic seiz...
- Associated Conditions
- Epilepsies, Generalized Tonic-Clonic Seizures, Partial-Onset Seizures, Myoclonic seizures
- Associated Therapies
- -
Study Evaluating the Safety and Efficacy of KTE-C19 in Adult Participants With Refractory Aggressive Non-Hodgkin Lymphoma
- Conditions
- Interventions
- Biological: Axicabtagene CiloleucelDrug: FludarabineDrug: CyclophosphamideDrug: LevetiracetamDrug: TocilizumabDrug: DexamethasoneDrug: DoxorubicinDrug: High-dose methylprednisoloneDrug: PrednisoneDrug: BendamustineDrug: VincristineDrug: RituximabDrug: IfosfamideDrug: CarboplatinDrug: MethylprednisoloneDrug: EtoposideDrug: GemcitabineDrug: OxaliplatinDrug: Cisplatin
- First Posted Date
- 2015-01-28
- Last Posted Date
- 2024-06-04
- Lead Sponsor
- Kite, A Gilead Company
- Target Recruit Count
- 307
- Registration Number
- NCT02348216
- Locations
- 🇺🇸
Hackensack University Medical Center, Hackensack, New Jersey, United States
🇺🇸University of California Los Angeles (UCLA), Santa Monica, California, United States
🇨🇦Princess Margaret, Toronto, Ontario, Canada
1 Week Versus 6 Weeks of Levetiracetam in Surgical Brain Tumor Patients
- Conditions
- Interventions
- First Posted Date
- 2015-01-08
- Last Posted Date
- 2021-12-15
- Lead Sponsor
- University of Florida
- Target Recruit Count
- 81
- Registration Number
- NCT02334722
- Locations
- 🇺🇸
University of Florida, Gainesville, Florida, United States
The Effects on Cognitive Function of Levetiracetam (Keppra®) Compared to Carbamazepine (Tegretol®, Carmazepine®) as Monotherapy for Children With Partial Seizure; A Multicentric Randomized Controlled Study
- First Posted Date
- 2014-08-05
- Last Posted Date
- 2014-12-09
- Lead Sponsor
- Yonsei University
- Target Recruit Count
- 75
- Registration Number
- NCT02208492
- Locations
- 🇰🇷
Severance hospital, Seoul, Korea, Republic of
A Study to Investigate the Safety of the Drugs Topiramate and Levetiracetam in Treating Children Recently Diagnosed With Epilepsy
- First Posted Date
- 2014-07-28
- Last Posted Date
- 2023-05-03
- Lead Sponsor
- Janssen Research & Development, LLC
- Target Recruit Count
- 63
- Registration Number
- NCT02201251
Efficacy of Levetiracetam in Oromandibular and Cranial Dystonia
- Conditions
- First Posted Date
- 2014-07-24
- Last Posted Date
- 2017-07-11
- Target Recruit Count
- 8
- Registration Number
- NCT02199509
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
Levetiracetam for Alzheimer's Disease-Associated Network Hyperexcitability
- First Posted Date
- 2013-12-06
- Last Posted Date
- 2022-05-16
- Lead Sponsor
- University of Minnesota
- Target Recruit Count
- 34
- Registration Number
- NCT02002819
- Locations
- 🇺🇸
University of Minnesota, Minneapolis, Minnesota, United States
🇺🇸UCSF, San Francisco, California, United States
Seizure Prophylaxis in Aneurysm Repair
- First Posted Date
- 2013-11-01
- Last Posted Date
- 2016-03-11
- Lead Sponsor
- Indiana University
- Target Recruit Count
- 17
- Registration Number
- NCT01974700
- Locations
- 🇺🇸
IU Health Methodist Hospital, Indianapolis, Indiana, United States
Established Status Epilepticus Treatment Trial
- Conditions
- Interventions
- First Posted Date
- 2013-10-10
- Last Posted Date
- 2021-06-14
- Lead Sponsor
- University of Virginia
- Target Recruit Count
- 478
- Registration Number
- NCT01960075
- Locations
- 🇺🇸
Children's Medical Center UTSW, Dallas, Texas, United States
🇺🇸Nationwide Children's Hospital, Columbus, Ohio, United States
🇺🇸UPMC Mercy Hospital, Pittsburgh, Pennsylvania, United States
Open-label, Randomized, Active-controlled Study of LEV Used as Monotherapy in Patients With Partial-Onset Seizures
- Conditions
- Interventions
- First Posted Date
- 2013-10-01
- Last Posted Date
- 2017-08-15
- Lead Sponsor
- UCB Pharma SA
- Target Recruit Count
- 436
- Registration Number
- NCT01954121
- Locations
- 🇨🇳
16, Changchun City, China
🇨🇳1, Guangzhou, China
🇨🇳20, Guangzhou, China
Seizure Prophylaxis With Levetiracetam in Aneurysmal Subarachnoid Hemorrhage - Pilot Study
- First Posted Date
- 2013-09-05
- Last Posted Date
- 2017-11-01
- Lead Sponsor
- Vanderbilt University Medical Center
- Registration Number
- NCT01935908
- Locations
- 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States
Drug Development Updates
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