Carbamazepine
- Generic Name
- Carbamazepine
- Brand Names
- Carbatrol, Carnexiv, Epitol, Equetro, Tegretol
- Drug Type
- Small Molecule
- Chemical Formula
- C15H12N2O
- CAS Number
- 298-46-4
- Unique Ingredient Identifier
- 33CM23913M
- Background
Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia. It was initially approved by the FDA in 1965. Aside from the above uses, this drug is also given to control the symptoms of bipolar 1. Interestingly, carbamazepine was the first anticonvulsant use...
- Indication
Carbamazepine is indicated for the treatment of epilepsy and pain associated with true trigeminal neuralgia. In particular, carbamazepine has shown efficacy in treating mixed seizures, partial seizures with complex symptoms, and generalized tonic-clonic seizures. Carbamazepine is also indicated for the treatment of manic episodes and mixed manic-depressive e...
- Associated Conditions
- Acute Mania, Alcohol Withdrawal Syndrome, Complex Partial Seizure Disorder, Generalized Tonic-Clonic Seizures, Mixed manic depressive episode, Pain, Partial Seizures With Secondary Generalization, Restless Legs Syndrome (RLS)
- Associated Therapies
- -
A Multi-part Study of ALG-000184 to Evaluate Safety, Tolerability, Pharmacokinetics and Drug-drug Interaction Potential After Single and Multiple Doses in Healthy Volunteers
- Conditions
- Interventions
- First Posted Date
- 2024-11-04
- Last Posted Date
- 2024-11-20
- Lead Sponsor
- Aligos Therapeutics
- Target Recruit Count
- 24
- Registration Number
- NCT06672900
- Locations
- 🇺🇸
PPD Austin Research Unit, Austin, Texas, United States
A Study to Investigate the Pharmacokinetics of AZD0780 When Administered Alone and in Combination With Itraconazole and Carbamazepine in Healthy Participants Aged 18 to 75 Years of Age
- Conditions
- Interventions
- First Posted Date
- 2024-11-04
- Last Posted Date
- 2024-11-04
- Lead Sponsor
- AstraZeneca
- Target Recruit Count
- 42
- Registration Number
- NCT06671405
- Locations
- 🇺🇸
Research Site, Brooklyn, Maryland, United States
A Drug-Drug Interaction Study of Carbamazepine and Opevesostat (MK-5684) in Healthy Adult Male Participants (MK-5684-012)
- Conditions
- Interventions
- First Posted Date
- 2024-10-09
- Last Posted Date
- 2024-11-15
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Target Recruit Count
- 14
- Registration Number
- NCT06633419
- Locations
- 🇺🇸
Celerion ( Site 0001), Tempe, Arizona, United States
Drug-Drug Interaction Study of Bomedemstat and Carbamazepine in Healthy Adult Participants (MK-3543-020)
- First Posted Date
- 2024-09-19
- Last Posted Date
- 2024-11-27
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Target Recruit Count
- 16
- Registration Number
- NCT06596668
- Locations
- 🇺🇸
Celerion, Inc. ( Site 0001), Tempe, Arizona, United States
A Study to Investigate the Pharmacokinetics of Midazolam After Repeated Doses of Camizestrant (AZD9833) and to Investigate the Pharmacokinetics of Camizestrant When Administered Alone and in Combination With Carbamazepine in Healthy Post-Menopausal Female Participants
- Conditions
- Interventions
- First Posted Date
- 2024-08-09
- Last Posted Date
- 2024-11-05
- Lead Sponsor
- AstraZeneca
- Target Recruit Count
- 40
- Registration Number
- NCT06547164
- Locations
- 🇬🇧
Research Site, Harrow, United Kingdom
A Drug-Drug Interaction (DDI) Study of Orforglipron With Carbamazepine in Healthy Participants
- First Posted Date
- 2024-04-17
- Last Posted Date
- 2024-07-26
- Lead Sponsor
- Eli Lilly and Company
- Target Recruit Count
- 30
- Registration Number
- NCT06370728
- Locations
- 🇺🇸
ICON Early Phase Services, San Antonio, Texas, United States
Pregabalin as an add-on Therapy to Carbamazepine in Trigeminal Neuralgia Patients
- Conditions
- Interventions
- First Posted Date
- 2024-04-10
- Last Posted Date
- 2024-06-10
- Lead Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
- Target Recruit Count
- 50
- Registration Number
- NCT06357260
- Locations
- 🇮🇳
PGIDS, Rohtak, Haryana, India
A Study to Learn About How Itraconazole and Carbamazepine Affect the Level of BAY2927088 in the Blood When These Drugs Are Taken Together by Healthy Participants
- Conditions
- Interventions
- First Posted Date
- 2024-04-05
- Last Posted Date
- 2024-06-20
- Lead Sponsor
- Bayer
- Target Recruit Count
- 30
- Registration Number
- NCT06348888
- Locations
- 🇺🇸
Parexel Baltimore - Early Phase Clinical Unit, Baltimore, Maryland, United States
A Study to Assess LY4100511 (DC-853) in Healthy Adult Participants
- Conditions
- Interventions
- First Posted Date
- 2024-04-03
- Last Posted Date
- 2024-05-10
- Target Recruit Count
- 50
- Registration Number
- NCT06345794
- Locations
- 🇺🇸
ICON San Antonio Clinical Research Unit, San Antonio, Texas, United States
Potential Drug Interaction Study Between Vemircopan and Rosuvastatin, Metformin, Levonorgestrel/Ethinyl Estradiol-containing Oral Contraceptives, and Carbamazepine
- Conditions
- Interventions
- First Posted Date
- 2023-10-06
- Last Posted Date
- 2024-05-16
- Lead Sponsor
- Alexion Pharmaceuticals, Inc.
- Target Recruit Count
- 60
- Registration Number
- NCT06071442
- Locations
- 🇺🇸
Research Site, Brooklyn, Maryland, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.