Carbamazepine
- Generic Name
- Carbamazepine
- Brand Names
- Carbatrol, Carnexiv, Epitol, Equetro, Tegretol
- Drug Type
- Small Molecule
- Chemical Formula
- C15H12N2O
- CAS Number
- 298-46-4
- Unique Ingredient Identifier
- 33CM23913M
- Background
Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia. It was initially approved by the FDA in 1965. Aside from the above uses, this drug is also given to control the symptoms of bipolar 1. Interestingly, carbamazepine was the first anticonvulsant use...
- Indication
Carbamazepine is indicated for the treatment of epilepsy and pain associated with true trigeminal neuralgia. In particular, carbamazepine has shown efficacy in treating mixed seizures, partial seizures with complex symptoms, and generalized tonic-clonic seizures. Carbamazepine is also indicated for the treatment of manic episodes and mixed manic-depressive e...
- Associated Conditions
- Acute Mania, Alcohol Withdrawal Syndrome, Complex Partial Seizure Disorder, Generalized Tonic-Clonic Seizures, Mixed manic depressive episode, Pain, Partial Seizures With Secondary Generalization, Restless Legs Syndrome (RLS)
- Associated Therapies
- -
Study to Evaluate the Effects of Cytochrome P450 (CYP) 3A4 Inducer Carbamazepine on Tavapadon Pharmacokinetics in Healthy Adult Participants
- First Posted Date
- 2022-10-17
- Last Posted Date
- 2023-04-20
- Lead Sponsor
- Cerevel Therapeutics, LLC
- Target Recruit Count
- 16
- Registration Number
- NCT05581823
- Locations
- 🇺🇸
Madison, Wisconsin, Madison, Wisconsin, United States
A Study of Ponesimod in Healthy Adult Participants
- First Posted Date
- 2022-09-23
- Last Posted Date
- 2024-03-29
- Lead Sponsor
- Janssen Pharmaceutica N.V., Belgium
- Target Recruit Count
- 28
- Registration Number
- NCT05552196
- Locations
- 🇧🇪
Clinical Pharmacology Unit, Merksem, Belgium
DDI Study of Evobrutinib and Carbamazepine
- First Posted Date
- 2022-02-21
- Last Posted Date
- 2022-08-22
- Lead Sponsor
- Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
- Target Recruit Count
- 14
- Registration Number
- NCT05248945
- Locations
- 🇩🇪
Nuvisan GmbH, Neu-Ulm, Bavaria, Germany
Tepotinib Drug-Drug Interaction Study With Carbamazepine in Healthy Participants
- First Posted Date
- 2022-01-28
- Last Posted Date
- 2024-03-08
- Lead Sponsor
- Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
- Target Recruit Count
- 18
- Registration Number
- NCT05213481
- Locations
- 🇩🇪
Nuvisan GmbH, Neu-Ulm, Germany
Study of the Effects of Itraconazole and Carbamazepine on LY3410738 in Healthy Participants
- First Posted Date
- 2022-01-25
- Last Posted Date
- 2022-12-28
- Lead Sponsor
- Eli Lilly and Company
- Target Recruit Count
- 27
- Registration Number
- NCT05205447
- Locations
- 🇺🇸
LabCorp CRU, Inc., Daytona Beach, Florida, United States
A Study to Learn What Happens to Elinzanetant in the Body When Taken With or Without Carbamazepine, and How Safe it is in Healthy Men and Women Aged 18 to 60 Years.
- Conditions
- Interventions
- First Posted Date
- 2021-08-31
- Last Posted Date
- 2022-02-25
- Lead Sponsor
- Bayer
- Target Recruit Count
- 16
- Registration Number
- NCT05028608
- Locations
- 🇩🇪
CRS Clinical-Research-Services Mannheim GmbH, Mannheim, Baden-Württemberg, Germany
Comparision Efficacy of Carbamazepine & Oxcarbazepine in the Treatment of Trigeminal Neuralgia- a Randomised Clinical Trial
- First Posted Date
- 2021-08-09
- Last Posted Date
- 2021-10-15
- Lead Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
- Target Recruit Count
- 132
- Registration Number
- NCT04996199
- Locations
- 🇮🇳
PGIDS, Rohtak, Haryana, India
🇮🇳Post Graduate Institute of Dental Sciences, Rohtak, Haryana, India
Drug-Drug Interaction Study Assessing Effect of Carbamazepine on PF-07321332 Boosted With Ritonavir
- Conditions
- Interventions
- First Posted Date
- 2021-07-14
- Last Posted Date
- 2023-10-10
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 12
- Registration Number
- NCT04962230
- Locations
- 🇺🇸
Pfizer New Haven Clinical Research Unit, New Haven, Connecticut, United States
Pharmacological Mechanisms of Low-intensity Focused Ultrasound for Motor Cortex Neuroplasticity
- Conditions
- Interventions
- First Posted Date
- 2021-06-11
- Last Posted Date
- 2022-05-25
- Lead Sponsor
- University Health Network, Toronto
- Target Recruit Count
- 20
- Registration Number
- NCT04923659
- Locations
- 🇨🇦
Toronto Western Hospital, Toronto, Ontario, Canada
A Study of LY3484356 in Healthy Female Participants
- Conditions
- Interventions
- First Posted Date
- 2021-04-12
- Last Posted Date
- 2022-05-02
- Lead Sponsor
- Eli Lilly and Company
- Target Recruit Count
- 82
- Registration Number
- NCT04840888
- Locations
- 🇺🇸
LabCorp CRU, Inc., Daytona Beach, Florida, United States
🇺🇸Covance Dallas, Dallas, Texas, United States
Drug Development Updates
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