Carbamazepine

Generic Name
Carbamazepine
Brand Names
Carbatrol, Carnexiv, Epitol, Equetro, Tegretol
Drug Type
Small Molecule
Chemical Formula
C15H12N2O
CAS Number
298-46-4
Unique Ingredient Identifier
33CM23913M
Background

Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia. It was initially approved by the FDA in 1965. Aside from the above uses, this drug is also given to control the symptoms of bipolar 1. Interestingly, carbamazepine was the first anticonvulsant use...

Indication

Carbamazepine is indicated for the treatment of epilepsy and pain associated with true trigeminal neuralgia. In particular, carbamazepine has shown efficacy in treating mixed seizures, partial seizures with complex symptoms, and generalized tonic-clonic seizures. Carbamazepine is also indicated for the treatment of manic episodes and mixed manic-depressive e...

Associated Conditions
Acute Mania, Alcohol Withdrawal Syndrome, Complex Partial Seizure Disorder, Generalized Tonic-Clonic Seizures, Mixed manic depressive episode, Pain, Partial Seizures With Secondary Generalization, Restless Legs Syndrome (RLS)
Associated Therapies
-
Clinical Trials
Related News

Pharmacovigilance in Gerontopsychiatric Patients

Phase 3
Terminated
Conditions
Dementia
Depression
Schizophrenia
Psychosomatic Disorders
Anxiety Disorders
Interventions
Drug: Phenobarbital
Drug: Phenytoin
Drug: Carbamazepine
Drug: Oxcarbazepine
Drug: Valproic Acid
Drug: Lamotrigine
Drug: Topiramate
Drug: Gabapentin
Drug: Levetiracetam
Drug: Pregabalin
Drug: Lacosamide
Drug: Clonazepam
Drug: Biperiden
Drug: Levomepromazine
Drug: Fluphenazine
Drug: Perphenazine
Drug: Perazine
Drug: Thioridazine
Drug: Haloperidol
Drug: Melperone
Drug: Pipamperone
Drug: Bromperidol
Drug: Benperidol
Drug: Sertindole
Drug: Ziprasidone
Drug: Flupentixol
Drug: Chlorprothixene
Drug: Zuclopenthixol
Drug: Fluspirilene
Drug: Pimozide
Drug: Clozapine
Drug: Olanzapine
Drug: Quetiapine
Drug: Sulpiride
Drug: Tiapride
Drug: Amisulpride
Drug: Prothipendyl
Drug: Risperidone
Drug: Aripiprazole
Drug: Paliperidone
Drug: Diazepam
Drug: Oxazepam
Drug: Lorazepam
Drug: Bromazepam
Drug: Clobazam
Drug: Alprazolam
Drug: Hydroxyzine
Drug: Buspirone
Drug: Chloral Hydrate
Drug: Flurazepam
Drug: Nitrazepam
Drug: Triazolam
Drug: Lormetazepam
Drug: Temazepam
Drug: Midazolam
Drug: Brotizolam
Drug: Zopiclone
Drug: Zolpidem
Drug: Zaleplon
Drug: Melatonin
Drug: Clomethiazole
Drug: Diphenhydramine
Drug: Promethazine
Drug: Imipramine
Drug: Clomipramine
Drug: Opipramol
Drug: Trimipramine
Drug: Amitriptyline
Drug: Nortriptyline
Drug: Doxepin
Drug: Maprotiline
Drug: Amitriptyline oxide
Drug: Fluoxetine
Drug: Citalopram
Drug: Paroxetine
Drug: Sertraline
Drug: Fluvoxamine
Drug: Escitalopram
Drug: Tranylcypromine
Drug: Moclobemide
Drug: Mianserin
Drug: Trazodone
Drug: Mirtazapine
Drug: Bupropion
Drug: Venlafaxine
Drug: Reboxetine
Drug: Duloxetine
Drug: Agomelatine
Drug: Pyritinol
Drug: Piracetam
Drug: Donepezil
Drug: Rivastigmine
Drug: Galantamine
Drug: Memantine
Drug: Nicergoline
Drug: Acamprosate
Drug: Lithium
First Posted Date
2015-03-02
Last Posted Date
2018-02-28
Lead Sponsor
Hannover Medical School
Target Recruit Count
407
Registration Number
NCT02374567
Locations
🇩🇪

Bezirkskrankenhaus Augsburg, Augsburg, Germany

🇩🇪

Krankenhaus Hedwigshöhe, Berlin, Germany

🇩🇪

Hannover Medical School, Hannover, Germany

and more 2 locations

Pharmacokinetic Interaction Study Between Eslicarbazepine Acetate and Carbamazepine

Phase 1
Completed
Conditions
Epilepsy
Interventions
Drug: BIA 2-093
Drug: Carbamazepine
First Posted Date
2014-11-06
Last Posted Date
2015-01-08
Lead Sponsor
Bial - Portela C S.A.
Target Recruit Count
43
Registration Number
NCT02284854

Effects of TPV/r on the Pharmacokinetics of Carbamazepine in Healthy Adult Volunteers

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: Carbamazepine
Drug: Tipranavir
Drug: Ritonavir
First Posted Date
2014-10-01
Last Posted Date
2014-10-01
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
28
Registration Number
NCT02253849

Carbamazapine for Inherited Erythromelalgia Patients With NaV1.7 Mutations

Phase 4
Completed
Conditions
Erythromelalgia
Interventions
Drug: Placebo
Drug: Carbamazepine
First Posted Date
2014-08-12
Last Posted Date
2017-06-06
Lead Sponsor
VA Connecticut Healthcare System
Target Recruit Count
2
Registration Number
NCT02214615
Locations
🇺🇸

VA Connecticut Healthcare System, West Haven, Connecticut, United States

🇺🇸

Yale University, New Haven, Connecticut, United States

Effect of Carbamazepine on Dolutegravir Pharmacokinetics in Healthy Adult Subjects

Phase 1
Completed
Conditions
Infection, Human Immunodeficiency Virus
Interventions
Drug: DTG
Drug: CBZ
First Posted Date
2013-10-23
Last Posted Date
2014-01-27
Lead Sponsor
ViiV Healthcare
Target Recruit Count
16
Registration Number
NCT01967771
Locations
🇺🇸

GSK Investigational Site, Overland Park, Kansas, United States

Open-label, Randomized, Active-controlled Study of LEV Used as Monotherapy in Patients With Partial-Onset Seizures

First Posted Date
2013-10-01
Last Posted Date
2017-08-15
Lead Sponsor
UCB Pharma SA
Target Recruit Count
436
Registration Number
NCT01954121
Locations
🇨🇳

16, Changchun City, China

🇨🇳

1, Guangzhou, China

🇨🇳

20, Guangzhou, China

and more 25 locations

A Phase 1 Open-Label Study to Evaluate the Effect of CYP450 and P-gp Inhibition and Induction on the Pharmacokinetics of Pomalidomide (CC-4047) in Healthy Male Subjects

First Posted Date
2012-10-16
Last Posted Date
2019-11-12
Lead Sponsor
Celgene
Target Recruit Count
32
Registration Number
NCT01707407
Locations
🇺🇸

Covance Research Unit, Inc, Madison, Wisconsin, United States

A Study to Investigate the Potential Pharmacokinetic Interactions Between Phenytoin or Carbamazepine and Telaprevir

First Posted Date
2012-07-10
Last Posted Date
2013-10-24
Lead Sponsor
Janssen Infectious Diseases BVBA
Target Recruit Count
24
Registration Number
NCT01635829

A Study of the Effect of Carbamazepine on the Pharmacokinetics of RO4917523 in Healthy Volunteers

Phase 1
Completed
Conditions
Healthy Volunteer
Interventions
Drug: Carbamazepine
Drug: RO4917523
First Posted Date
2012-06-27
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
16
Registration Number
NCT01629368

Efficacy and Safety Evaluation of Carbamazepine for Prevention of Chemotherapy-induced Nausea and Vomiting

First Posted Date
2012-04-20
Last Posted Date
2012-04-24
Lead Sponsor
Faculdade de Medicina do ABC
Target Recruit Count
43
Registration Number
NCT01581918
Locations
🇧🇷

ABC Medical School, Santo André, São Paulo, Brazil

© Copyright 2024. All Rights Reserved by MedPath
HomeTerms & ConditionsPrivacy Policy