A barbituric acid derivative that acts as a nonselective central nervous system depressant. It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
For the treatment of all types of seizures except absence seizures.
Kafrelsheikh University, Tanta, Kafrelsheikh, Egypt
OSF Saint Francis Medical Center, Peoria, Illinois, United States
University of Tennessee Medical Center, Knoxville, Tennessee, United States
Red Cross War Memorial Children's Hospital, Cape Town, Western Cape, South Africa
University of Maryland Medical Center, Baltimore, Maryland, United States
AP-HP Cochin, Paris, France
Cairo University Children's Hospital (Abulreesh), Cairo Governorate, Egypt
Xuanwu Hospital, Beijing, Beijing, China
Xijing Hospital, Shanxi, Xi'an, China
Zhongshan Hospital, Xiamen University, Xiamen, Fujian, China
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