Primidone
- Generic Name
- Primidone
- Brand Names
- Mysoline
- Drug Type
- Small Molecule
- Chemical Formula
- C12H14N2O2
- CAS Number
- 125-33-7
- Unique Ingredient Identifier
- 13AFD7670Q
- Background
Primidone is an anticonvulsant used to treat essential tremor as well as grand mal, psychomotor, and focal epileptic seizures. Primidone was developed by J Yule Bogue and H C Carrington in 1949.
Primidone was granted FDA Approval on 8 March 1954.
- Indication
Primidone is commonly indicated for the management of grand mal, psychomotor, and focal epileptic seizures. In addition, it has also been studied and utilized as an effective management of essential tremor.
- Associated Conditions
- Essential Tremor, Generalized Tonic-Clonic Seizures, Partial-Onset Seizures, Temporal Lobe Epilepsy (TLE)
Pathophysiology of Tremor-modulating Mechanisms of Propranolol and Primidone in Essential Tremor
- First Posted Date
- 2021-01-05
- Last Posted Date
- 2023-04-13
- Lead Sponsor
- University Medical Centre Ljubljana
- Target Recruit Count
- 61
- Registration Number
- NCT04692844
- Locations
- 🇸🇮
Departmet of Neurology, University Medical Centre Ljubljana, Ljubljana, Slovenia
Population Pharmacokinetics of Antiepileptic in Pediatrics
- Conditions
- Epilepsy
- Interventions
- Biological: brivaracétamBiological: pregabalineOther: genetic polymorphisms
- First Posted Date
- 2017-06-22
- Last Posted Date
- 2024-10-30
- Lead Sponsor
- Assistance Publique - Hôpitaux de Paris
- Target Recruit Count
- 1000
- Registration Number
- NCT03196466
- Locations
- 🇫🇷
AP-HP Cochin, Paris, France
Effect of Primidone on Platelet Responsiveness in Patients Determined to be Clopidogrel Resistant
- Conditions
- Clopidogrel ResistanceSecondary Stroke Prevention
- Interventions
- First Posted Date
- 2013-12-11
- Last Posted Date
- 2016-08-03
- Lead Sponsor
- Dent Neuroscience Research Center
- Registration Number
- NCT02008123
- Locations
- 🇺🇸
Dent Neurologic Institute, Amherst, New York, United States
Bioequivalence Study of Primidone Tablets 50 mg of Dr. Reddy's Under Fasting Conditions
- First Posted Date
- 2010-05-27
- Last Posted Date
- 2010-05-27
- Lead Sponsor
- Dr. Reddy's Laboratories Limited
- Target Recruit Count
- 24
- Registration Number
- NCT01132040
- Locations
- 🇮🇳
Bioserve Clinical Research Pvt. Ltd,, HYD, Andhra Pradesh, India
Fasted Bioequivalence Study of Primidone Tablets and Mysoline Tablets
- Conditions
- Therapeutic Equivalency
- Interventions
- First Posted Date
- 2008-05-28
- Last Posted Date
- 2010-01-20
- Lead Sponsor
- Mutual Pharmaceutical Company, Inc.
- Target Recruit Count
- 22
- Registration Number
- NCT00685165
Drug Development Updates
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