Ketorolac

Generic Name
Ketorolac
Brand Names
Acular, Acuvail, Omidria, Readysharp Anesthetics Plus Ketorolac, Sprix, Toradol, Toronova Suik
Drug Type
Small Molecule
Chemical Formula
C15H13NO3
CAS Number
74103-06-3
Unique Ingredient Identifier
YZI5105V0L
Background

Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution.
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Indication

Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and has antipyretic, analgesic and anti-inflammatory properties. It is indicated for short term management of acute pain that requires the calibre of pain management offered by opioids. Clinicians may choose to initiate ketorolac to manage post-operative pain, spinal and soft tissue pain, rheumatoid...

Associated Conditions
Acute Migraine, Eye Pain, Inflammation, Macular Edema, Cystoid, Ocular Itching, Pericarditis Acute, Pseudophakic Cystoid Macular Oedema, Severe Acute Pain, Acute, moderate Pain, Chronic aphakic cystoid macular edema, Intraoperative miosis, Postoperative ocular pain
Associated Therapies
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The Role of Prostaglandins in the Progression of Diabetic Retinopathy

Phase 1
Withdrawn
Conditions
Interventions
First Posted Date
2012-06-01
Last Posted Date
2017-02-23
Lead Sponsor
Vanderbilt University
Registration Number
NCT01609881
Locations
🇺🇸

Vanderbilt Eye Institute, Nashville, Tennessee, United States

Intramuscular Ketorolac Versus Oral Ibuprofen for Pain Relief in First Trimester Suction Curettage

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2012-05-10
Last Posted Date
2014-07-02
Lead Sponsor
Planned Parenthood League of Massachusetts
Target Recruit Count
94
Registration Number
NCT01595282
Locations
🇺🇸

Planned Parenthood League of Massachusetts, Boston, Massachusetts, United States

Intravenous Ketorolac and Metoclopramide for Pediatric Migraine in the Emergency Department

First Posted Date
2012-05-10
Last Posted Date
2015-01-26
Lead Sponsor
University of Alberta
Target Recruit Count
56
Registration Number
NCT01596166
Locations
🇨🇦

Stollery Children's Hospital, Edmonton, Alberta, Canada

🇨🇦

Alberta Children's Hospital, Calgary, Alberta, Canada

A Brain Imaging Study of Opioid (Morphine) and Non-opioid (Ketorolac) Conditioning Effects

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2012-04-12
Last Posted Date
2018-06-29
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
51
Registration Number
NCT01576276
Locations
🇺🇸

Massachusetts General Hospital, Charlestown, Massachusetts, United States

Comparison of Topical Ketorolac 0,4% Versus Placebo in Cataract Surgery

First Posted Date
2012-03-02
Last Posted Date
2014-12-04
Lead Sponsor
University of Campinas, Brazil
Target Recruit Count
80
Registration Number
NCT01542190
Locations
🇧🇷

Unicamp, Campinas, Sao Paulo, Brazil

Prochlorperazine Versus Prochlorperazine & Ketorolac in Treatment of Pediatric Migraine in the Emergency Department

Phase 4
Withdrawn
Conditions
Interventions
First Posted Date
2012-02-17
Last Posted Date
2014-06-24
Lead Sponsor
Akron Children's Hospital
Registration Number
NCT01534806
Locations
🇺🇸

Akron Children's Hospital, Akron, Ohio, United States

KITS Study -Ketorolac In Tonsillectomy Surgery: a Double Blinded, Randomized Clinical Trial

First Posted Date
2011-12-23
Last Posted Date
2020-03-25
Lead Sponsor
University of Alberta
Target Recruit Count
121
Registration Number
NCT01498796
Locations
🇨🇦

Stollery Children's Hospital, Edmonton, Alberta, Canada

Comparison Of Ketorolac Tromethamine Versus Naproxen For Moderate to Severe Back Pain Treatment

Phase 3
Completed
Conditions
Interventions
First Posted Date
2011-11-16
Last Posted Date
2021-02-24
Lead Sponsor
EMS
Target Recruit Count
83
Registration Number
NCT01471886
Locations
🇧🇷

IOT - Instituto de Ortopedia e Traumatologia, Sao Paulo, SP, Brazil

Comparison Of Ketorolac Tromethamine Oral Drops Versus Naproxen For Moderate to Severe Back Pain Treatment

Phase 3
Completed
Conditions
Interventions
First Posted Date
2011-11-16
Last Posted Date
2021-02-24
Lead Sponsor
EMS
Target Recruit Count
78
Registration Number
NCT01471899
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