Salmeterol

Generic Name
Salmeterol
Brand Names
Advair, Airduo, Airduo Respiclick, Serevent, Serevent Diskus, Wixela
Drug Type
Small Molecule
Chemical Formula
C25H37NO4
CAS Number
89365-50-4
Unique Ingredient Identifier
2I4BC502BT
Background

Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD. It has a longer duration of action than the short-acting beta-2 adrenergic receptor agonist, salbutamol. Salmeterol was first described in the literature in 1988. Salmeterol's structure i...

Indication

用于哮喘(包括夜间哮喘和运动性哮喘)、喘息性支气管炎和可逆性气道阻塞。

Associated Conditions
Asthma, Chronic Obstructive Pulmonary Disease (COPD), Exercise-Induced Bronchospasm
Associated Therapies
-

Evaluate Onset of Effect in Patients With Chronic Obstructive Pulmonary Disease (COPD) Treated With Formoterol Turbuhaler®

First Posted Date
2010-01-13
Last Posted Date
2012-10-25
Lead Sponsor
AstraZeneca
Target Recruit Count
109
Registration Number
NCT01048333
Locations
🇸🇪

Research Site, Lund, Sweden

Validation of a New Shortness of Breath With Daily Activities Questionnaire in Patients With Chronic Obstructive Pulmonary Disease

First Posted Date
2009-09-25
Last Posted Date
2018-08-29
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
366
Registration Number
NCT00984659
Locations
🇺🇸

GSK Investigational Site, Spokane, Washington, United States

A Study To Investigate The Safety, Toleration And Efficacy of PF00610355 In Chronic Obstructive Pulmonary Disease (COPD) Patients.

First Posted Date
2008-12-15
Last Posted Date
2019-02-06
Lead Sponsor
Pfizer
Target Recruit Count
405
Registration Number
NCT00808288
Locations
🇹🇷

Pfizer Investigational Site, Izmir, Turkey

The Effects of Montelukast on Smokers With Asthma

First Posted Date
2008-07-09
Last Posted Date
2012-05-16
Lead Sponsor
Inje University
Target Recruit Count
105
Registration Number
NCT00712335
Locations
🇰🇷

Asthma and Allergy Center, Inje University Sanggye Paik Hospital, Seoul, Korea, Republic of

The Effects of Different Long-acting Bronchodilator Medications on Asthma Patients With Different Genetic Variations

First Posted Date
2008-06-27
Last Posted Date
2017-05-31
Lead Sponsor
Brigham and Women's Hospital
Target Recruit Count
255
Registration Number
NCT00706446
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

🇺🇸

Brigham and Women's Hospital, Boston, Massachusetts, United States

Tiotropium and Salmeterol PK Study in COPD Patients

Phase 3
Completed
Conditions
First Posted Date
2008-05-07
Last Posted Date
2014-05-16
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
50
Registration Number
NCT00673478
Locations
🇧🇪

1184.24.32001 Boehringer Ingelheim Investigational Site, Genk, Belgium

🇧🇪

1184.24.32002 Boehringer Ingelheim Investigational Site, Hasselt, Belgium

🇳🇱

1184.24.31001 Boehringer Ingelheim Investigational Site, Heerlen, Netherlands

Tiotropium/Salmeterol Inhalation Powder in COPD

First Posted Date
2008-04-29
Last Posted Date
2023-11-07
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
207
Registration Number
NCT00668772
Locations
🇱🇻

1184.15.37153 Boehringer Ingelheim Investigational Site, Tukums, Latvia

🇺🇸

1184.15.01071 Boehringer Ingelheim Investigational Site, Mobile, Alabama, United States

🇩🇰

1184.15.45054 Boehringer Ingelheim Investigational Site, Aalborg, Denmark

and more 61 locations

Tiotropium/Salmeterol Inhalation Powder (Spiriva Handihaler and Salmeterol Polyethylene (PE) Capsule) in Chronic Obstructive Pulmonary Disease (COPD)

First Posted Date
2008-04-21
Last Posted Date
2023-08-23
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
220
Registration Number
NCT00662740
Locations
🇺🇸

1184.14.01006 Boehringer Ingelheim Investigational Site, Winter Park, Florida, United States

🇺🇸

1184.14.01015 Boehringer Ingelheim Investigational Site, South Bend, Indiana, United States

🇳🇱

1184.14.31001 Boehringer Ingelheim Investigational Site, Veldhoven, Netherlands

and more 69 locations

Confirmatory Dose Finding Study of 2 Dosages of CHF 4226 pMDI (Carmoterol) in Patients With COPD

First Posted Date
2008-03-21
Last Posted Date
2010-08-27
Lead Sponsor
Chiesi Farmaceutici S.p.A.
Target Recruit Count
57
Registration Number
NCT00640484
Locations
🇺🇸

Spartanburg Medical Research, Spartanburg, South Carolina, United States

🇺🇸

UCLA David Geffen School of Medicine, Los Angeles, California, United States

🇺🇸

Horizon Clinical Research Associates, PLLC, Gilbert, Arizona, United States

and more 12 locations

Study of Indacaterol Dosed in the Evening in Patients With Chronic Obstructive Pulmonary Disease (COPD)

First Posted Date
2008-02-14
Last Posted Date
2011-08-17
Lead Sponsor
Novartis
Target Recruit Count
96
Registration Number
NCT00615030
Locations
🇪🇸

Novartis Investigative Site, Barcelona, Spain

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