Tiotropium
- Generic Name
- Tiotropium
- Brand Names
- Inspiolto Respimat, Spiriva, Spiriva Respimat, Stiolto
- Drug Type
- Small Molecule
- Chemical Formula
- C19H22NO4S2
- CAS Number
- 186691-13-4
- Unique Ingredient Identifier
- 0EB439235F
- Background
Tiotropium is a long-acting, antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and asthma. Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and bronchodilation.
...
- Indication
Tiotropium powder for inhalation is indicated for the maintenance of bronchospasm in COPD and to prevent exacerbations of COPD. A combination tiotropium and olodaterol metered inhalation spray is indicated for maintenance of COPD. A tiotropium inhalation spray is indicated for the maintenance of bronchospasm in COPD, to prevent exacerbations of COPD, and to ...
- Associated Conditions
- Asthma, Bronchitis, Bronchoconstriction, Chronic Bronchitis, Chronic Obstructive Pulmonary Disease (COPD), Emphysema, Exacerbation of COPD
- Associated Therapies
- -
Effect of Tiotropium on Eye Findings in the Treatment of Chronic Obstructive Pulmonary Disease
- Conditions
- Interventions
- First Posted Date
- 2024-07-29
- Last Posted Date
- 2024-07-29
- Lead Sponsor
- Giresun University
- Target Recruit Count
- 108
- Registration Number
- NCT06525051
- Locations
- 🇹🇷
Giresun Training and Research Hospital, Giresun, Gi̇resun, Turkey
ANTES B+ Clinical Trial
- Conditions
- Interventions
- Drug: Trelegy Ellipta 100/62.5/25Mcg Inh 30DDrug: BrimicaDrug: DuaklirDrug: UltibroDrug: UlunarDrug: XoternaDrug: AnoroDrug: LaventairDrug: Spiolto RespimatDrug: YanimoDrug: ForadilDrug: BroncoralDrug: Formoterol stadaDrug: OxisDrug: FormatrisDrug: Formoterol AldoDrug: OnbrezDrug: OslifDrug: HirobrizDrug: StriverdiDrug: BeglanDrug: BetamicanDrug: InaspirDrug: SereventDrug: SoltelDrug: EkliraDrug: BretarisDrug: SeebriDrug: TovanorDrug: EnurevDrug: SpirivaDrug: TavulusDrug: SirkavaDrug: BraltusDrug: GregalDrug: IncruseDrug: Rolufta
- First Posted Date
- 2024-02-28
- Last Posted Date
- 2024-03-05
- Lead Sponsor
- Fundacio Privada Mon Clinic Barcelona
- Target Recruit Count
- 1028
- Registration Number
- NCT06282861
- Locations
- 🇪🇸
Hospital Clínic Barcelona, Barcelona, Catalunya, Spain
Efficacy and Safety of Indacaterol vs Tiotropium in Women With COPD Secondary to Biomass Exposure
- First Posted Date
- 2022-08-18
- Last Posted Date
- 2022-08-18
- Target Recruit Count
- 97
- Registration Number
- NCT05506865
- Locations
- 🇲🇽
Instituto Nacional de Enfermedades Respiratorias, "Ismael Cosío Villegas", Mexico, City, Mexico
Exacerbation Risk in Asthma
- Conditions
- Interventions
- First Posted Date
- 2022-08-15
- Last Posted Date
- 2024-04-01
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 1899
- Registration Number
- NCT05501639
- Locations
- 🇺🇸
eMax Health, White Plains, New York, United States
Replication of the INSPIRE Trial in Healthcare Claims Data
- Conditions
- Interventions
- First Posted Date
- 2022-01-05
- Last Posted Date
- 2023-07-27
- Lead Sponsor
- Brigham and Women's Hospital
- Target Recruit Count
- 98278
- Registration Number
- NCT05179512
- Locations
- 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
Phase 4 COPD and Suboptimal Inspiratory Flow Rate
- Conditions
- Interventions
- First Posted Date
- 2021-12-21
- Last Posted Date
- 2024-12-20
- Lead Sponsor
- Theravance Biopharma
- Target Recruit Count
- 404
- Registration Number
- NCT05165485
- Locations
- 🇺🇸
Theravance Biopharma Investigational Site site 2, Clearwater, Florida, United States
🇺🇸Theravance Biopharma Investigational Site, Cudahy, Wisconsin, United States
🇺🇸Theravance Biopharma Investigational Site #2, Spartanburg, South Carolina, United States
Replication of the POET-COPD Trial in Healthcare Claims Data
- Conditions
- Interventions
- First Posted Date
- 2021-10-19
- Last Posted Date
- 2023-07-27
- Lead Sponsor
- Brigham and Women's Hospital
- Target Recruit Count
- 8716
- Registration Number
- NCT05083429
- Locations
- 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
Early Intervention Efficacy in COPD
- Conditions
- Interventions
- First Posted Date
- 2020-01-30
- Last Posted Date
- 2022-06-14
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 6788
- Registration Number
- NCT04249310
- Locations
- 🇯🇵
Nara Medical University, Nara, Japan
Effect of Charcoal on Gastrointestinal Absorption of Tiotropium
- First Posted Date
- 2019-05-10
- Last Posted Date
- 2019-09-23
- Lead Sponsor
- Orion Corporation, Orion Pharma
- Target Recruit Count
- 20
- Registration Number
- NCT03945344
- Locations
- 🇫🇮
Clinical Pharmacology Unit, Espoo, Finland
A Randomized Study, Comparing Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) Single Inhaler Triple Therapy, Versus Multiple Inhaler Therapy (Budesonide/Formoterol Plus Tiotropium) in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
- Conditions
- Interventions
- First Posted Date
- 2018-03-27
- Last Posted Date
- 2020-10-28
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 729
- Registration Number
- NCT03478683
- Locations
- 🇳🇱
GSK Investigational Site, Zutphen, Netherlands
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.