Erythropoietin

Generic Name
Erythropoietin
Brand Names
Procrit, Eprex, Epprex, Epoetin Alfa Hexal, Silapo, Biopoin, Abseamed, Eporatio, NeoRecormon, Epogen, Retacrit
Drug Type
Biotech
Chemical Formula
-
CAS Number
11096-26-7
Unique Ingredient Identifier
64FS3BFH5W
Background

Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells. It works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow . Epoetin alfa (Epoge) was developed by Amgen Inc. in 1983 as the first rhEPO commercialized in the United States, followed by other alf...

Indication

用于肾功能不全合并的贫血，艾滋病本身或因治疗引起的贫血，恶性肿瘤伴发的贫血及风湿性贫血等。另外，为择期手术储存自体血而反复采血的患者，同时应用本品可预防发生贫血。

Associated Conditions
Anemia, Blood Loss During Surgery, Anemia caused by Zidovudine
Associated Therapies
-
Clinical Trials
Related News

A Study of Epoetin Beta (NeoRecormon) in Participants With Solid Tumors or Hematologic Malignancies

Phase 4
Completed
Conditions
Anemia
Interventions
Drug: Epoetin beta
First Posted Date
2015-09-30
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
54
Registration Number
NCT02564094

A Study of Epoetin Beta (NeoRecormon) in Participants With Solid Tumors

Phase 4
Completed
Conditions
Anemia
Interventions
Drug: Epoetin beta
First Posted Date
2015-09-18
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
28
Registration Number
NCT02554942

Erythropoietin + Iron Therapy for Anemic Patients Undergoing Aortic Valve Replacement

Phase 3
Completed
Conditions
Anemia
Aortic Stenosis
Interventions
Drug: Placebo
Drug: Erythropoietin
First Posted Date
2015-03-17
Last Posted Date
2018-07-17
Lead Sponsor
Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
Target Recruit Count
117
Registration Number
NCT02390102
Locations
🇨🇦

Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Quebec, Canada

Erythropoietin in Methanol Associated Optic Neuropathy: A Phase-2 Clinical Trial (EPO-MAON Study)

First Posted Date
2015-03-03
Last Posted Date
2020-03-10
Lead Sponsor
Tehran University of Medical Sciences
Target Recruit Count
24
Registration Number
NCT02376881
Locations
🇮🇷

Farabi Hospital, Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of

Effect of Recombinant Erythropoietin on Numbers of Circulating Endothelial Progenitor Cells in Subacute TBI

Phase 2
Withdrawn
Conditions
Traumatic Brain Injury
Interventions
Drug: Erythropoietin
First Posted Date
2014-05-28
Last Posted Date
2019-01-18
Lead Sponsor
Uniformed Services University of the Health Sciences
Registration Number
NCT02148367
Locations
🇺🇸

National Institutes of Health, Clinical Center., Bethesda, Maryland, United States

A Study of Epoetin Beta Treatment in Anemic Participants With Myelodysplastic Syndrome (MDS)

Phase 4
Completed
Conditions
Myelodysplastic Syndromes
Interventions
Drug: Epoetin beta
First Posted Date
2014-05-22
Last Posted Date
2020-04-24
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
100
Registration Number
NCT02145026
Locations
🇹🇭

Siriraj Hospital; Division of Hematology, Department of Medicine, Bangkok, Thailand

🇹🇭

Thammasart Chalermprakiert Hospital, Thammasart Uni; Hematology, Pathumthani, Thailand

🇹🇭

Srinagarind Hospital, Khon Kaen Uni ; Dept of Medicine, Khon Kaen, Thailand

and more 7 locations

Neuroprotective Role of Erythropoietin in Perinatal Asphyxia

Phase 2
Completed
Conditions
Perinatal Asphyxia
Interventions
Drug: Erythropoietin
First Posted Date
2013-12-05
Last Posted Date
2016-10-14
Lead Sponsor
Sheri Kashmir Institute of Medical Sciences
Target Recruit Count
100
Registration Number
NCT02002039
Locations
🇮🇳

Sheri-Kashmir Institute of Medical Sciences, Srinagar, Jammu and kashmir, India

Neonatal Erythropoietin And Therapeutic Hypothermia Outcomes in Newborn Brain Injury (NEATO)

First Posted Date
2013-08-01
Last Posted Date
2020-07-13
Lead Sponsor
University of California, San Francisco
Target Recruit Count
50
Registration Number
NCT01913340
Locations
🇺🇸

Washington University, Saint Louis, Missouri, United States

🇺🇸

Arkansas Children's Hospital Research Institute, Little Rock, Arkansas, United States

🇺🇸

Stanford University, Palo Alto, California, United States

and more 4 locations

Oxidative Stress and Inflammation Caused by Intravenous Iron in Crohn's Disease Patients With Iron Deficiency Anemia

First Posted Date
2013-04-04
Last Posted Date
2013-11-27
Lead Sponsor
Jinling Hospital, China
Target Recruit Count
387
Registration Number
NCT01823029
Locations
🇨🇳

General Surgery Institute,Jinling Hospital, Nanjing, Jiangsu, China

An Observational Study of Epoetin Beta (NeoRecormon) in Participants With Cancer Receiving Chemotherapy

Completed
Conditions
Anemia
Interventions
Drug: Epoetin beta
First Posted Date
2013-03-12
Last Posted Date
2016-08-19
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1167
Registration Number
NCT01809314
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